Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1614990..1615714 Replicon chromosome
Accession NZ_CP017481
Organism Pectobacterium polaris strain NIBIO1006

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BJJ97_RS07325 Protein ID WP_095993506.1
Coordinates 1614990..1615301 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BJJ97_RS07330 Protein ID WP_095993507.1
Coordinates 1615298..1615714 (+) Length 139 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ97_RS07310 1611015..1612550 - 1536 WP_095993503.1 carbohydrate porin -
BJJ97_RS07315 1612750..1613673 - 924 WP_095993504.1 aminoimidazole riboside kinase -
BJJ97_RS07320 1614280..1614831 + 552 WP_095993505.1 polymer-forming cytoskeletal protein -
BJJ97_RS07325 1614990..1615301 + 312 WP_095993506.1 type II toxin-antitoxin system HigB family toxin Toxin
BJJ97_RS07330 1615298..1615714 + 417 WP_095993507.1 helix-turn-helix domain-containing protein Antitoxin
BJJ97_RS07335 1615922..1616380 + 459 WP_095993508.1 hypothetical protein -
BJJ97_RS07340 1616473..1617825 - 1353 WP_095993509.1 aspartate aminotransferase family protein -
BJJ97_RS07345 1617880..1619148 - 1269 WP_095993510.1 MFS transporter -
BJJ97_RS07350 1619302..1619748 + 447 WP_095701372.1 helix-turn-helix transcriptional regulator -
BJJ97_RS07355 1619758..1620204 + 447 WP_095993511.1 YhbP family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(83-136)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12436.31 Da        Isoelectric Point: 10.0380

>T66882 WP_095993506.1 NZ_CP017481:1614990-1615301 [Pectobacterium polaris]
MHVISRAPFDTATTQFPNQATALADLYRVIKREMYATPDDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKI
FIKHITSHAEYDRLTEYYRRNKE

Download         Length: 312 bp

>T66882 NZ_CP017481:1614990-1615301 [Pectobacterium polaris]
ATGCATGTTATTTCGCGGGCACCTTTCGACACTGCAACCACTCAGTTTCCGAATCAGGCTACAGCACTTGCTGACCTATA
TCGGGTTATCAAACGCGAAATGTATGCAACACCGGACGATATGAAAAAACGTTTCCCTAGCCTAGATAGGATGAAATACC
GGGAAAAATGGTGGGTTATTGATATTGGTGGCGGGCATCTTCGAGTGATGTTTTTTGCTGATTTTGAGCGGGGGAAAATC
TTCATCAAGCACATTACATCCCATGCAGAGTATGACAGGCTGACAGAGTATTACCGGAGGAATAAAGAATGA

Antitoxin


Download         Length: 139 a.a.        Molecular weight: 15391.63 Da        Isoelectric Point: 4.6581

>AT66882 WP_095993507.1 NZ_CP017481:1615298-1615714 [Pectobacterium polaris]
MMYADAIKAANNLTSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSPLIDMLTAKIDKYENDAPEFAAFNERVKALPAGI
ALLRVLMDQHQLTQSDFEAEIGKKSLVSRILNGERTLTLDHMRALAKRFDIPVSAFVD

Download         Length: 417 bp

>AT66882 NZ_CP017481:1615298-1615714 [Pectobacterium polaris]
ATGATGTACGCAGACGCTATCAAGGCAGCTAACAACCTGACGAGTATCGTACCATTCCTCGGAGGCAGCACCTCTCGTAA
GGATTATGAGGATGCGCTGAAACTCACTGAATACCTGATCGAGAGTGAGCCTGATAGTCCGCTAATCGATATGCTGACTG
CCAAAATTGACAAATACGAGAATGATGCACCGGAGTTTGCAGCCTTCAACGAACGTGTTAAAGCACTCCCGGCCGGTATC
GCTTTACTGCGCGTCCTTATGGATCAGCATCAGCTAACGCAGAGTGATTTTGAAGCTGAGATTGGTAAAAAGTCTCTGGT
ATCCCGCATTCTAAACGGTGAGCGCACTCTAACGCTTGATCACATGAGAGCGCTTGCTAAACGATTCGATATTCCCGTGA
GTGCTTTTGTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References