66877

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1018885..1020236 Replicon chromosome
Accession NZ_CP017481
Organism Pectobacterium polaris strain NIBIO1006

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag BJJ97_RS04630 Protein ID WP_095993214.1
Coordinates 1019196..1020236 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID A0A6P1S6U4
Locus tag BJJ97_RS04625 Protein ID WP_039483284.1
Coordinates 1018885..1019199 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJJ97_RS04605 1014502..1016190 + 1689 WP_095993210.1 ABC transporter ATP-binding protein -
BJJ97_RS04610 1016222..1017256 + 1035 WP_095993211.1 putative FMN-dependent luciferase-like monooxygenase -
BJJ97_RS04615 1017253..1018386 + 1134 WP_095993212.1 alkylhydroperoxidase domain protein -
BJJ97_RS04620 1018685..1018900 + 216 WP_125460915.1 helix-turn-helix domain-containing protein -
BJJ97_RS04625 1018885..1019199 + 315 WP_039483284.1 HipA N-terminal domain-containing protein Antitoxin
BJJ97_RS04630 1019196..1020236 + 1041 WP_095993214.1 HipA domain-containing protein Toxin
BJJ97_RS04635 1020296..1020919 - 624 WP_095993215.1 LysE family translocator -
BJJ97_RS04640 1021182..1021937 + 756 WP_095993216.1 thiol:disulfide interchange protein DsbG -
BJJ97_RS04645 1021971..1022876 - 906 WP_095993217.1 siderophore-interacting protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39435.33 Da        Isoelectric Point: 6.6637

>T66877 WP_095993214.1 NZ_CP017481:1019196-1020236 [Pectobacterium polaris]
MTRCRILLTPLTHEEEIATGYSRKGLKHLTGSTHASSTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVLEERAFTVVDH
QGLCILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
VGEKFGKIHTDGRQYVSYERLASFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
ADAIETTLRCYRHRLKLMSILDAERI

Download         Length: 1041 bp

>T66877 NZ_CP017481:1019196-1020236 [Pectobacterium polaris]
ATGACAAGATGTCGAATTTTGCTGACACCGCTGACACACGAAGAAGAAATCGCCACAGGCTATAGCCGTAAAGGGTTAAA
GCATCTGACGGGATCAACGCATGCCTCCTCGACCTTACGTTTCACCCGCCAGCAATTTATGCACGACCTGCCACAAGCAC
AGAAAGGCATGAGCATCTCTGGCTATCAGCCCAAAATTCAGATGGTATTAGAAGAACGGGCGTTTACCGTCGTTGATCAT
CAAGGGCTGTGCATCCTCAAGCCTTCTCCGATTGAATTTCCCCATTTGGCAGAAAACGAACACGCCACGATGACATTAAT
GGCACGCCTGGGATTTGCCGTTCCACCACACGGGTTACTCCGTTTTAAACCGGAGCAGGCTGATGACGAACCTGAGTTTG
CTTTCGTTATTAAGCGCTTCGACCGCGACGAAAAAACGGGTCACCCTATCCATCAGGAACAGTTGGACGGTGCGATGGGG
GTCGGTGAAAAATTCGGTAAAATACACACGGATGGCAGACAATACGTCAGTTATGAGCGGTTGGCTTCATTCCTTAGCAA
ACACGTTAATGACAATATCGTCTTCAAAATAGATCTGTTTCGCCGTATCGCTTACGCCTACATGCTGGGTAACAACGACA
TGCACCTGCGTAATTTTGGTTTGATACATTCGCGCTCAGGTTCGTTAATGCTGGCTCCCATTTATGATTTTGTTTCCGTC
GCCCCCTATCCCACCTATTTTTCTTCCTGCTTCATGGCATTGCCGCTGCTGATTCAAGAAGAGGGGGATGAAGCACTCGC
GCCAGGATTTGAAACCGCATACGGAGAATACCTTGGTATGGATTTCATTCTATTCGGGCAACGTATCGGGCTGAGTGAAA
ACCTGACCAAAAAACTACTGGCAGACTTTCTCAAAGAAGCTGAATGTGTTGAATCAACCTATCGGGATTCCTTTATGCCT
GCGGATGCTATTGAGACAACGCTGCGGTGCTATCGACACCGCCTGAAGCTTATGAGCATTCTCGATGCAGAACGGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11868.62 Da        Isoelectric Point: 8.3774

>AT66877 WP_039483284.1 NZ_CP017481:1018885-1019199 [Pectobacterium polaris]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFHSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp

>AT66877 NZ_CP017481:1018885-1019199 [Pectobacterium polaris]
ATGCGCCGTCAAGTAAAGGTCTATCTTTACGGTGTCCACATCGGCCAGTTAAGTCAGGACGATGAAGGTTATCTGTTTGA
ATATAAAAAGTCCTACATCGGCCCGCCATTATCATTGAGCCTACCGATACAGACCGGCACATTTCACAGCAAAACATTAC
CGCCCTACTTTGCCTCGTTAGCTCCCGAAGGCTGGCTGCGGCGACAGTACAGCCAGCTTCAGCATCTGGATGAGAAGGAT
TTATTTGGCATCCTCATTCAAAATGGTAAGAACCTGATCGGTGCCGTGCAACTGATCGCGGAGGATAAGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6P1S6U4

References