Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3816763..3817268 Replicon chromosome
Accession NZ_CP017296
Organism Pseudomonas fluorescens strain Pt14

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0W0MVT7
Locus tag BH711_RS17190 Protein ID WP_014719853.1
Coordinates 3817014..3817268 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID I4K3F7
Locus tag BH711_RS17185 Protein ID WP_003194039.1
Coordinates 3816763..3817017 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BH711_RS17170 3812201..3814102 + 1902 WP_038451460.1 alkaline phosphatase family protein -
BH711_RS17175 3814241..3815254 + 1014 WP_038451462.1 sensor domain-containing diguanylate cyclase -
BH711_RS17180 3815365..3816618 + 1254 WP_038451464.1 aspartate aminotransferase family protein -
BH711_RS17185 3816763..3817017 + 255 WP_003194039.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BH711_RS17190 3817014..3817268 + 255 WP_014719853.1 Txe/YoeB family addiction module toxin Toxin
BH711_RS17195 3817367..3818083 + 717 WP_014719854.1 hypothetical protein -
BH711_RS17200 3818094..3819215 - 1122 WP_014719855.1 aminotransferase class V-fold PLP-dependent enzyme -
BH711_RS17205 3819217..3820419 - 1203 WP_019817486.1 MFS transporter -
BH711_RS17210 3820419..3821669 - 1251 WP_069868754.1 ATP-grasp domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9977.51 Da        Isoelectric Point: 8.0456

>T66442 WP_014719853.1 NZ_CP017296:3817014-3817268 [Pseudomonas fluorescens]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFGGVGKPEPLKHNLSGFWSRRITAEHRLVYGIEDDEVQILMC
RYHY

Download         Length: 255 bp

>T66442 NZ_CP017296:3817014-3817268 [Pseudomonas fluorescens]
ATGAAAATACTCTTTACCCCTGAAGGCTGGGACGACTACCTCTGGTTTCAACAGAACGACAAAGCCGGGCTCAAGCGCAT
CAATCTCTTGATCAAGGCCATACAAAGAGACCCGTTCGGCGGCGTGGGGAAGCCTGAACCCCTCAAACATAACCTGAGTG
GTTTCTGGTCTCGACGAATCACCGCGGAGCATCGTTTGGTTTATGGCATCGAGGATGATGAAGTACAAATATTGATGTGC
CGCTACCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9576.93 Da        Isoelectric Point: 7.2034

>AT66442 WP_003194039.1 NZ_CP017296:3816763-3817017 [Pseudomonas fluorescens]
METINYTNARAHLSETMDRVNDDHVPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRR
LIEE

Download         Length: 255 bp

>AT66442 NZ_CP017296:3816763-3817017 [Pseudomonas fluorescens]
ATGGAAACTATCAACTACACCAACGCCCGAGCCCATCTGTCCGAAACGATGGACCGCGTCAACGATGATCACGTCCCACT
TCTACTGACTCGACAAAAAGGCGAGCCCGTGGTGATGATCTCGTTATCAGAGTTCAATGCTCTGGAAGAGACGGCTTACC
TGCTGCGCTCGCCTAAAAATGCCGAACGTCTCATTAACTCAGTCAACAGCTTACGAGCAGGCAAAGCCAAGCCAAGGCGG
TTGATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0W0MVT7

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0MVN5

References