Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2547731..2548385 Replicon chromosome
Accession NZ_CP017296
Organism Pseudomonas fluorescens strain Pt14

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BH711_RS11275 Protein ID WP_038450524.1
Coordinates 2547731..2548081 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0W0N117
Locus tag BH711_RS11280 Protein ID WP_014718915.1
Coordinates 2548071..2548385 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BH711_RS11265 2544490..2546022 + 1533 WP_014718913.1 NADH-quinone oxidoreductase subunit M -
BH711_RS11270 2546030..2547493 + 1464 WP_003174731.1 NADH-quinone oxidoreductase subunit NuoN -
BH711_RS11275 2547731..2548081 + 351 WP_038450524.1 hypothetical protein Toxin
BH711_RS11280 2548071..2548385 + 315 WP_014718915.1 XRE family transcriptional regulator Antitoxin
BH711_RS11285 2548444..2549196 - 753 WP_038450526.1 outer membrane beta-barrel protein -
BH711_RS11290 2549322..2550155 - 834 WP_038450528.1 arylamine N-acetyltransferase -
BH711_RS11295 2550276..2550512 + 237 WP_014718918.1 hypothetical protein -
BH711_RS11300 2550543..2550737 - 195 WP_005789138.1 hypothetical protein -
BH711_RS11305 2550750..2550929 - 180 WP_014718919.1 hypothetical protein -
BH711_RS11310 2551043..2551564 + 522 WP_014718920.1 DUF3087 family protein -
BH711_RS11315 2551595..2552455 - 861 WP_020302316.1 Dyp-type peroxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13790.82 Da        Isoelectric Point: 9.8857

>T66439 WP_038450524.1 NZ_CP017296:2547731-2548081 [Pseudomonas fluorescens]
MDALFIELPAFERYRKDYLSDELFQGFQQELMKNPEAGDVIEGTGGLRKVRFIDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQNDLAPQHKKALKHMLVREIKARMHNET

Download         Length: 351 bp

>T66439 NZ_CP017296:2547731-2548081 [Pseudomonas fluorescens]
ATGGATGCTCTATTTATCGAACTGCCGGCATTCGAGCGGTATCGCAAAGACTATCTGAGTGACGAGCTTTTCCAGGGTTT
TCAACAGGAGTTAATGAAAAACCCCGAAGCAGGAGACGTGATCGAAGGGACGGGCGGGTTGAGGAAGGTTCGCTTCATCG
ATGAACGACGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTATTACTGGTGGTCAGGCGGTACGCAATTCTGGTTA
TTCACCTTGTACGGCAAACACGAACAAAACGACCTGGCACCGCAACACAAGAAAGCCCTTAAACACATGCTGGTCAGGGA
AATCAAAGCGAGAATGCACAATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11755.58 Da        Isoelectric Point: 10.6525

>AT66439 WP_014718915.1 NZ_CP017296:2548071-2548385 [Pseudomonas fluorescens]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT66439 NZ_CP017296:2548071-2548385 [Pseudomonas fluorescens]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGCTTCGACGCTTTGGCCGATGAACGCCAGGGTAAAATCACCCTGCG
CAACCACAAAGTGCACCTCAACAAGCTGGCGCCGCTTACCGCAGACGAGGTGATCGCTGTGCGCCAGCAACTCAACCTCT
CCCGGTCGGTATTCGCCATGTATCTGCGTACCAACACCCGCACCCTGGAGAACTGGGAACAAGGCCGGGCCAAACCCAAC
GCCCAGGCCGTCACCCTGATCCGCCTGGTGGCGCGCTTTCCGGAAACCGTGGCGCAACTGGCCGCACTGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0N117

References