Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2490896..2491080 Replicon chromosome
Accession NZ_CP017115
Organism Staphylococcus aureus strain FORC_045

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FORC45_RS13055 Protein ID WP_000482647.1
Coordinates 2490973..2491080 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2490896..2490956 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC45_RS13030 2486370..2486537 - 168 WP_001790576.1 hypothetical protein -
FORC45_RS13040 2486768..2488501 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
FORC45_RS13045 2488526..2490289 - 1764 WP_088607410.1 ABC transporter ATP-binding protein/permease -
- 2490896..2490956 + 61 - - Antitoxin
FORC45_RS13055 2490973..2491080 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
FORC45_RS13060 2491214..2491600 - 387 WP_000779360.1 flippase GtxA -
FORC45_RS13065 2491858..2493000 + 1143 WP_001176871.1 glycerate kinase -
FORC45_RS13070 2493060..2493719 + 660 WP_000831301.1 membrane protein -
FORC45_RS13075 2493901..2495112 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FORC45_RS13080 2495235..2495708 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T66048 WP_000482647.1 NZ_CP017115:c2491080-2490973 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T66048 NZ_CP017115:c2491080-2490973 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT66048 NZ_CP017115:2490896-2490956 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References