Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2211160..2211357 Replicon chromosome
Accession NZ_CP017115
Organism Staphylococcus aureus strain FORC_045

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FORC45_RS11530 Protein ID WP_001802298.1
Coordinates 2211253..2211357 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2211160..2211198 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC45_RS11510 2207344..2208009 - 666 WP_001024095.1 SDR family oxidoreductase -
FORC45_RS11515 2208161..2208481 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FORC45_RS11520 2208483..2209463 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
FORC45_RS11525 2209729..2210820 + 1092 WP_000495683.1 hypothetical protein -
- 2211160..2211198 + 39 - - Antitoxin
FORC45_RS11530 2211253..2211357 - 105 WP_001802298.1 hypothetical protein Toxin
FORC45_RS11540 2212037..2212195 + 159 WP_001792784.1 hypothetical protein -
FORC45_RS11550 2212854..2213711 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
FORC45_RS11555 2213779..2214561 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T66046 WP_001802298.1 NZ_CP017115:c2211357-2211253 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T66046 NZ_CP017115:c2211357-2211253 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT66046 NZ_CP017115:2211160-2211198 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References