Detailed information of TA system TA066022

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2189047..2189376
• Replicon: chromosome
• Accession: NZ_CP017112
• Organism: Bacillus subtilis strain BS16045

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: BS16045_RS21950
• Protein ID: WP_080010576.1
• Coordinates: 2189047..2189298 (-)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2189276..2189376 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BS16045_RS11285	2184275..2184496	-	222	WP_032677253.1	helix-turn-helix transcriptional regulator	-
BS16045_RS11290	2184570..2184902	-	333	WP_019712280.1	hypothetical protein	-
BS16045_RS11295	2184972..2185169	-	198	WP_032677195.1	hypothetical protein	-
BS16045_RS11300	2185272..2185598	-	327	WP_003230992.1	hypothetical protein	-
BS16045_RS22595	2185631..2185804	-	174	WP_196219421.1	hypothetical protein	-
BS16045_RS11305	2185839..2186048	-	210	WP_069322700.1	hypothetical protein	-
BS16045_RS11310	2186045..2186302	-	258	WP_069322701.1	hypothetical protein	-
BS16045_RS11315	2186840..2187169	-	330	WP_069322702.1	hypothetical protein	-
BS16045_RS11320	2187515..2188732	-	1218	WP_069322703.1	hypothetical protein	-
BS16045_RS11325	2188814..2189002	-	189	WP_003230987.1	hypothetical protein	-
BS16045_RS21950	2189047..2189298	-	252	WP_080010576.1	hypothetical protein	Toxin
-	2189276..2189376	+	101	-	-	Antitoxin
BS16045_RS11330	2189317..2189493	-	177	WP_069322704.1	hypothetical protein	-
-	2189434..2189534	+	101	NuclAT_0	-	-
-	2189434..2189534	+	101	NuclAT_0	-	-
-	2189434..2189534	+	101	NuclAT_0	-	-
-	2189434..2189534	+	101	NuclAT_0	-	-
BS16045_RS11335	2190453..2190647	+	195	WP_003230986.1	hypothetical protein	-
BS16045_RS11340	2190687..2193206	+	2520	WP_019712270.1	hypothetical protein	-
BS16045_RS11345	2193450..2193728	+	279	WP_004399274.1	HU-related DNA-binding protein HupN	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2118917..2284254	165337

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 10071.13 Da
• Isoelectric Point: 10.0301

>T66022 WP_080010576.1 NZ_CP017112:c2189298-2189047 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEAQTLINIIFIVTCIIAILLWIIYFVFLKLRN
KSH

Nucleotide

• Length: 252 bp

>T66022 NZ_CP017112:c2189298-2189047 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATTAAGGATTACTTCAGCAGCGAAGCACAAACACTAA
TCAATATAATATTCATAGTCACATGTATCATTGCCATATTGTTGTGGATCATCTATTTTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT66022 NZ_CP017112:2189276-2189376 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATATGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin