Detailed information of TA system TA066019

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2047772..2048087
• Replicon: chromosome
• Accession: NZ_CP017112
• Organism: Bacillus subtilis strain BS16045

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: BS16045_RS22345
• Protein ID: WP_120322743.1
• Coordinates: 2047772..2047933 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2047914..2048087 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BS16045_RS10320	2043001..2043336	+	336	WP_069322638.1	hypothetical protein	-
BS16045_RS10325	2043383..2046988	-	3606	WP_004399367.1	membrane protein	-
BS16045_RS22345	2047772..2047933	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2047914..2048087	-	174	-	-	Antitoxin
BS16045_RS10335	2048202..2049044	-	843	WP_003231327.1	hypothetical protein	-
BS16045_RS10340	2049244..2049702	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
BS16045_RS10345	2049712..2051514	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
BS16045_RS10350	2051616..2052173	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2034238..2057504	23266

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T66019 WP_120322743.1 NZ_CP017112:2047772-2047933 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T66019 NZ_CP017112:2047772-2047933 [Bacillus subtilis]
ATTTCCTGTACAGTAAGTTTTGCTCACTCGAGGGAGTCTTGCTCATCCCCTAATGAAAGGGGTGATGCTATGTCAACATT
CCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAATAGACCTCCCTT
GA

Antitoxin

Nucleotide

• Length: 174 bp

>AT66019 NZ_CP017112:c2048087-2047914 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin