Detailed information of TA system TA065939

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 141935..142117
• Replicon: chromosome
• Accession: NZ_CP017094
• Organism: Staphylococcus aureus strain 2148.C01

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7U45_RS15215
• Protein ID: WP_001801861.1
• Coordinates: 142022..142117 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	141935..141994 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7U45_RS00915	141073..141450	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
A7U45_RS00920	141644..141820	+	177	Protein_130	transposase	-
A7U45_RS00925	141798..141899	-	102	WP_001791893.1	hypothetical protein	-
-	141935..141994	+	60	-	-	Antitoxin
A7U45_RS15215	142022..142117	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7U45_RS00935	142320..142463	+	144	WP_001549059.1	transposase	-
A7U45_RS00945	143067..143450	+	384	WP_000070811.1	hypothetical protein	-
A7U45_RS00950	143461..143637	+	177	WP_000375476.1	hypothetical protein	-
A7U45_RS00955	143639..143824	+	186	WP_000809857.1	hypothetical protein	-
A7U45_RS00960	143938..144579	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
A7U45_RS00965	144797..145348	-	552	WP_000414205.1	hypothetical protein	-
A7U45_RS00970	145446..145790	-	345	WP_000627551.1	DUF3969 family protein	-
A7U45_RS00975	145831..146457	-	627	Protein_140	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	123415..168156	44741

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T65939 WP_001801861.1 NZ_CP017094:c142117-142022 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T65939 NZ_CP017094:c142117-142022 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT65939 NZ_CP017094:141935-141994 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin