Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2523165..2523349 Replicon chromosome
Accession NZ_CP017091
Organism Staphylococcus aureus strain ISU926 isolate ST398

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag A2U18_RS13135 Protein ID WP_000482647.1
Coordinates 2523242..2523349 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2523165..2523225 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A2U18_RS13110 2518619..2518786 - 168 WP_001798790.1 hypothetical protein -
A2U18_RS13120 2519017..2520750 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
A2U18_RS13125 2520775..2522538 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2523165..2523225 + 61 - - Antitoxin
A2U18_RS13135 2523242..2523349 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
A2U18_RS13140 2523483..2523869 - 387 WP_000779355.1 flippase GtxA -
A2U18_RS13145 2524136..2525278 + 1143 WP_001176859.1 glycerate kinase -
A2U18_RS13150 2525338..2525997 + 660 WP_000831300.1 hypothetical protein -
A2U18_RS13155 2526185..2527396 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
A2U18_RS13160 2527519..2527992 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T65936 WP_000482647.1 NZ_CP017091:c2523349-2523242 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T65936 NZ_CP017091:c2523349-2523242 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT65936 NZ_CP017091:2523165-2523225 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References