Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 376461..376994 Replicon chromosome
Accession NZ_CP017075
Organism Novosphingobium resinovorum strain SA1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1D8A0G5
Locus tag BES08_RS01705 Protein ID WP_069707532.1
Coordinates 376725..376994 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1D8A0H1
Locus tag BES08_RS01700 Protein ID WP_069707531.1
Coordinates 376461..376715 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BES08_RS01685 371483..373411 - 1929 WP_069707529.1 EAL domain-containing protein -
BES08_RS01690 373603..376083 + 2481 WP_069707530.1 ATP-dependent helicase HrpB -
BES08_RS01695 376129..376407 + 279 WP_008830939.1 ETC complex I subunit -
BES08_RS01700 376461..376715 + 255 WP_069707531.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BES08_RS01705 376725..376994 + 270 WP_069707532.1 Txe/YoeB family addiction module toxin Toxin
BES08_RS01715 377249..379153 + 1905 WP_037519972.1 DNA polymerase III subunit gamma/tau -
BES08_RS01720 379155..379490 + 336 WP_008830943.1 YbaB/EbfC family nucleoid-associated protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10502.94 Da        Isoelectric Point: 10.0505

>T65868 WP_069707532.1 NZ_CP017075:376725-376994 [Novosphingobium resinovorum]
VKIVFASRTWEDYQHWVANDRTTLERLNALIEQCRRTPFKGTGKPEPLKGELQGWWSRRINQADRLVYRVAGSGAEQRLE
IAQCRFHYV

Download         Length: 270 bp

>T65868 NZ_CP017075:376725-376994 [Novosphingobium resinovorum]
GTGAAAATCGTTTTCGCCTCTCGCACCTGGGAGGATTACCAGCACTGGGTCGCCAATGACCGTACCACGCTGGAAAGGCT
GAATGCGCTGATCGAACAGTGCCGCCGGACGCCTTTCAAGGGGACCGGAAAGCCGGAGCCGCTCAAGGGCGAATTGCAGG
GCTGGTGGTCGCGGCGGATCAATCAGGCGGACAGGCTGGTCTATCGCGTCGCCGGAAGTGGAGCGGAGCAGCGGCTGGAA
ATCGCCCAATGCCGATTCCATTACGTCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9319.53 Da        Isoelectric Point: 4.7628

>AT65868 WP_069707531.1 NZ_CP017075:376461-376715 [Novosphingobium resinovorum]
MEVLPFSEARANFKALMDHVVDDRSPVIVTRQKAEAVVVVSLSDWNAMAETMHLVSTPANSTRLRDSVRELDGGEGQERN
LVQP

Download         Length: 255 bp

>AT65868 NZ_CP017075:376461-376715 [Novosphingobium resinovorum]
ATGGAAGTGCTCCCGTTCTCCGAAGCGCGCGCCAATTTCAAGGCGCTGATGGATCATGTGGTGGACGATCGTTCACCCGT
CATCGTTACACGCCAAAAGGCGGAAGCGGTGGTCGTGGTCTCGCTGTCCGACTGGAACGCAATGGCCGAAACCATGCACC
TTGTCTCGACCCCGGCGAATTCGACCCGCCTGCGCGATTCCGTTCGGGAACTCGATGGGGGGGAAGGGCAGGAACGCAAT
CTCGTCCAGCCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D8A0G5

Antitoxin

Source ID Structure
AlphaFold DB A0A1D8A0H1

References