65644

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 195929..196656 Replicon chromosome
Accession NZ_CP016950
Organism Cupriavidus taiwanensis strain SWF66294

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag A9P79_RS12875 Protein ID WP_240073478.1
Coordinates 195929..196225 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag A9P79_RS12880 Protein ID WP_240073480.1
Coordinates 196258..196656 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9P79_RS12860 (A9P79_12640) 191604..192572 + 969 WP_240073477.1 M48 family metallopeptidase -
A9P79_RS12865 193422..194627 + 1206 Protein_180 S8 family serine peptidase -
A9P79_RS12870 (A9P79_12650) 194810..195757 - 948 WP_115679169.1 N-acetyl-gamma-glutamyl-phosphate reductase -
A9P79_RS12875 (A9P79_12655) 195929..196225 + 297 WP_240073478.1 type II toxin-antitoxin system MqsR family toxin Toxin
A9P79_RS12880 (A9P79_12660) 196258..196656 + 399 WP_240073480.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
A9P79_RS12885 (A9P79_12665) 196678..197454 - 777 WP_025586397.1 exodeoxyribonuclease III -
A9P79_RS12890 (A9P79_12670) 197482..198177 + 696 WP_240073482.1 orotate phosphoribosyltransferase -
A9P79_RS12895 (A9P79_12675) 198268..199575 + 1308 WP_240073483.1 patatin-like phospholipase family protein -
A9P79_RS12900 (A9P79_12680) 199618..200427 - 810 WP_240073485.1 polyphosphate kinase 2 family protein -
A9P79_RS12905 (A9P79_12685) 200524..201390 - 867 WP_240073487.1 diaminopimelate epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(73-108)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11301.20 Da        Isoelectric Point: 10.0669

>T65644 WP_240073478.1 NZ_CP016950:195929-196225 [Cupriavidus taiwanensis]
MEKGTAHYKLRHVKALLQAGKMEMTFAAYSHAAMMGLRWTGVRDILSRLEPADFYKSMTTYEDHRIWQDVYRPVTPHGAL
YVKLTVASEVLVVSFKPR

Download         Length: 297 bp

>T65644 NZ_CP016950:195929-196225 [Cupriavidus taiwanensis]
ATGGAGAAGGGGACGGCGCATTACAAACTGCGGCATGTGAAGGCCCTGTTGCAGGCGGGCAAGATGGAGATGACGTTTGC
GGCGTATTCCCACGCCGCGATGATGGGCCTGCGTTGGACCGGGGTGCGCGACATCCTCTCGCGCCTCGAGCCGGCGGATT
TCTACAAGAGCATGACAACGTACGAAGACCATCGGATCTGGCAGGACGTCTACCGGCCCGTCACGCCGCATGGCGCTTTG
TATGTGAAGCTCACCGTTGCCAGCGAGGTGTTGGTCGTTTCCTTCAAGCCAAGGTAA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14707.95 Da        Isoelectric Point: 6.9072

>AT65644 WP_240073480.1 NZ_CP016950:196258-196656 [Cupriavidus taiwanensis]
MKCPECGGAELVAGMRDMPYTYRGETTVIPNVSGQWCPKCGEGVLPRDSDWVSEAMLAFNRQVNAALVDPSYITEVRKKL
RLDQREAAEIFGGGVNAFSRYETGRTKPPLALVKLLRLLDRHPELLEEIRAA

Download         Length: 399 bp

>AT65644 NZ_CP016950:196258-196656 [Cupriavidus taiwanensis]
ATGAAGTGTCCCGAGTGCGGTGGCGCGGAACTGGTGGCGGGAATGCGCGACATGCCCTATACGTACCGCGGTGAAACCAC
GGTGATCCCGAATGTATCCGGGCAATGGTGCCCCAAGTGCGGCGAGGGCGTGCTGCCCCGTGACAGCGACTGGGTGAGCG
AGGCGATGCTTGCCTTCAACCGGCAAGTCAATGCCGCCCTCGTCGATCCGTCCTATATCACCGAAGTCCGCAAGAAGCTC
CGCCTGGACCAGCGCGAGGCCGCCGAAATCTTCGGCGGTGGCGTCAATGCGTTCTCGCGGTACGAAACCGGGCGGACCAA
GCCGCCACTGGCGCTGGTGAAGCTGCTGCGGCTGCTGGACCGCCACCCGGAGCTGCTGGAGGAAATCCGGGCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References