Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4193561..4194063 Replicon chromosome
Accession NZ_CP016935
Organism Yersinia enterocolitica strain YE7

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BED34_RS19875 Protein ID WP_049528435.1
Coordinates 4193561..4193815 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7U7IZ70
Locus tag BED34_RS19880 Protein ID WP_049528437.1
Coordinates 4193812..4194063 (-) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BED34_RS19865 4188651..4190783 - 2133 WP_069009560.1 TonB-dependent siderophore receptor -
BED34_RS19870 4191202..4193537 + 2336 Protein_3804 mechanosensitive ion channel family protein -
BED34_RS19875 4193561..4193815 - 255 WP_049528435.1 Txe/YoeB family addiction module toxin Toxin
BED34_RS19880 4193812..4194063 - 252 WP_049528437.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
BED34_RS19885 4194194..4196979 - 2786 Protein_3807 insulinase family protein -
BED34_RS19890 4196964..4198709 - 1746 WP_162489085.1 ABC transporter ATP-binding protein/permease -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-84)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10098.54 Da        Isoelectric Point: 8.4816

>T65538 WP_049528435.1 NZ_CP016935:c4193815-4193561 [Yersinia enterocolitica]
VRIIFSSCSWEDYLYWQQTDKEILKRINELVKNIQRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYEVSGDNLLIAAC
RYHY

Download         Length: 255 bp

>T65538 NZ_CP016935:c4193815-4193561 [Yersinia enterocolitica]
GTGAGAATTATATTTTCCAGTTGTTCTTGGGAGGATTATCTTTATTGGCAACAAACGGATAAGGAAATCCTCAAACGCAT
TAATGAGTTAGTAAAAAATATTCAAAGAACGCCATTTGAGGGAAAGGGTAAACCGGAACCCCTTAAACATAATCTGGCAG
GGTTCTGGTCACGGAGGATTACAGAAGAGCACAGACTTGTTTATGAGGTTTCCGGTGATAATTTATTAATTGCTGCTTGT
CGTTACCATTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9463.66 Da        Isoelectric Point: 4.4878

>AT65538 WP_049528437.1 NZ_CP016935:c4194063-4193812 [Yersinia enterocolitica]
MRTISYSEARQNLSTTMVQTVEDRAPILITRQNGTSCVLMSLEEYESLEETAYLLRSPSNAKHLMDSIEELRAGKGIQRE
LEE

Download         Length: 252 bp

>AT65538 NZ_CP016935:c4194063-4193812 [Yersinia enterocolitica]
ATGAGAACAATTAGTTATAGTGAGGCGCGCCAGAATTTGTCGACAACGATGGTGCAAACGGTTGAGGATCGAGCCCCCAT
CCTCATCACTCGTCAAAATGGGACTTCTTGTGTTCTTATGTCACTTGAAGAATATGAATCATTGGAAGAAACTGCTTATT
TACTGCGCTCACCATCAAACGCGAAGCATTTGATGGACTCAATTGAAGAGTTGAGAGCAGGAAAAGGAATTCAAAGGGAA
CTTGAAGAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7U7IZ70

References