Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 404876..405527 Replicon plasmid unnamed1
Accession NZ_CP016890
Organism Pantoea agglomerans strain C410P1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BEE12_RS21150 Protein ID WP_069026837.1
Coordinates 405183..405527 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BEE12_RS21145 Protein ID WP_069026836.1
Coordinates 404876..405190 (-) Length 105 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEE12_RS21120 400778..401080 - 303 WP_069026834.1 type 1 fimbrial protein -
BEE12_RS21125 401569..401988 - 420 WP_031594127.1 VOC family protein -
BEE12_RS21130 402027..402908 - 882 WP_031594128.1 LysR family transcriptional regulator -
BEE12_RS21135 403054..403905 + 852 WP_069026835.1 MBL fold metallo-hydrolase -
BEE12_RS21140 403996..404666 - 671 Protein_367 hypothetical protein -
BEE12_RS21145 404876..405190 - 315 WP_069026836.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
BEE12_RS21150 405183..405527 - 345 WP_069026837.1 toxin Toxin
BEE12_RS21155 405617..406528 - 912 WP_069026838.1 LysR family transcriptional regulator -
BEE12_RS21160 406626..407684 + 1059 WP_069026944.1 SDR family oxidoreductase -
BEE12_RS21165 407742..408620 - 879 WP_033768811.1 23S rRNA pseudouridine(2604) synthase RluF -
BEE12_RS21170 408724..409194 - 471 WP_031594134.1 GNAT family N-acetyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..543504 543504


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(18-100)


Sequences


Toxin        


Download         Length: 115 a.a.        Molecular weight: 13486.26 Da        Isoelectric Point: 9.6381

>T65401 WP_069026837.1 NZ_CP016890:c405527-405183 [Pantoea agglomerans]
MDALFIELSSFQKYRADYLNDDQYRLFQNMLLADPEKGDVIPDTGGLRKVRFRDERRHKGARGGIRVIYYWTNTQGQFIL
FTIYDKDQRDDLTRQQRDALATALNVIKKGLRHD

Download         Length: 345 bp

>T65401 NZ_CP016890:c405527-405183 [Pantoea agglomerans]
ATGGACGCACTATTCATCGAACTTTCCAGCTTCCAGAAATACCGGGCTGATTATCTGAATGATGATCAGTACAGGCTGTT
TCAGAACATGTTGCTGGCTGACCCTGAGAAGGGCGATGTGATACCCGATACCGGCGGACTGCGTAAAGTTCGCTTCAGGG
ATGAGCGCCGACACAAGGGCGCACGTGGCGGGATCAGGGTTATCTATTACTGGACCAACACACAAGGCCAATTCATCCTG
TTTACCATCTACGATAAAGATCAACGCGACGATTTGACCAGGCAACAGCGTGATGCCCTGGCGACCGCGCTGAATGTGAT
CAAAAAAGGACTGAGACATGACTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12022.84 Da        Isoelectric Point: 9.8806

>AT65401 WP_069026836.1 NZ_CP016890:c405190-404876 [Pantoea agglomerans]
MTERDIFSELMTGMQELKDHQEGKITLKSYKVTKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRARP
NAQAVLLIRMVQQNPETLKTLAKL

Download         Length: 315 bp

>AT65401 NZ_CP016890:c405190-404876 [Pantoea agglomerans]
ATGACTGAACGCGATATCTTCAGTGAACTGATGACGGGTATGCAGGAGCTTAAGGATCATCAGGAGGGCAAAATTACGCT
TAAGAGTTATAAGGTCACTAAGCGTGCCCCTGTAACTATTGCGCCGCAGGAGTTACGCGACGTACGCGAAAAACTGAACC
TCTCACAGGCCGTATTCGCCCATTATCTTCATACTGGCGAAACGACATATCAAAACTGGGAACAGGGCAGGGCGAGACCT
AACGCCCAGGCTGTTTTACTGATCCGCATGGTGCAGCAGAACCCAGAAACGCTGAAGACGCTCGCGAAGCTCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References