Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/MqsA(antitoxin) |
Location | 404876..405527 | Replicon | plasmid unnamed1 |
Accession | NZ_CP016890 | ||
Organism | Pantoea agglomerans strain C410P1 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | BEE12_RS21150 | Protein ID | WP_069026837.1 |
Coordinates | 405183..405527 (-) | Length | 115 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | BEE12_RS21145 | Protein ID | WP_069026836.1 |
Coordinates | 404876..405190 (-) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BEE12_RS21120 | 400778..401080 | - | 303 | WP_069026834.1 | type 1 fimbrial protein | - |
BEE12_RS21125 | 401569..401988 | - | 420 | WP_031594127.1 | VOC family protein | - |
BEE12_RS21130 | 402027..402908 | - | 882 | WP_031594128.1 | LysR family transcriptional regulator | - |
BEE12_RS21135 | 403054..403905 | + | 852 | WP_069026835.1 | MBL fold metallo-hydrolase | - |
BEE12_RS21140 | 403996..404666 | - | 671 | Protein_367 | hypothetical protein | - |
BEE12_RS21145 | 404876..405190 | - | 315 | WP_069026836.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
BEE12_RS21150 | 405183..405527 | - | 345 | WP_069026837.1 | toxin | Toxin |
BEE12_RS21155 | 405617..406528 | - | 912 | WP_069026838.1 | LysR family transcriptional regulator | - |
BEE12_RS21160 | 406626..407684 | + | 1059 | WP_069026944.1 | SDR family oxidoreductase | - |
BEE12_RS21165 | 407742..408620 | - | 879 | WP_033768811.1 | 23S rRNA pseudouridine(2604) synthase RluF | - |
BEE12_RS21170 | 408724..409194 | - | 471 | WP_031594134.1 | GNAT family N-acetyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | iroN | 1..543504 | 543504 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 13486.26 Da Isoelectric Point: 9.6381
>T65401 WP_069026837.1 NZ_CP016890:c405527-405183 [Pantoea agglomerans]
MDALFIELSSFQKYRADYLNDDQYRLFQNMLLADPEKGDVIPDTGGLRKVRFRDERRHKGARGGIRVIYYWTNTQGQFIL
FTIYDKDQRDDLTRQQRDALATALNVIKKGLRHD
MDALFIELSSFQKYRADYLNDDQYRLFQNMLLADPEKGDVIPDTGGLRKVRFRDERRHKGARGGIRVIYYWTNTQGQFIL
FTIYDKDQRDDLTRQQRDALATALNVIKKGLRHD
Download Length: 345 bp
>T65401 NZ_CP016890:c405527-405183 [Pantoea agglomerans]
ATGGACGCACTATTCATCGAACTTTCCAGCTTCCAGAAATACCGGGCTGATTATCTGAATGATGATCAGTACAGGCTGTT
TCAGAACATGTTGCTGGCTGACCCTGAGAAGGGCGATGTGATACCCGATACCGGCGGACTGCGTAAAGTTCGCTTCAGGG
ATGAGCGCCGACACAAGGGCGCACGTGGCGGGATCAGGGTTATCTATTACTGGACCAACACACAAGGCCAATTCATCCTG
TTTACCATCTACGATAAAGATCAACGCGACGATTTGACCAGGCAACAGCGTGATGCCCTGGCGACCGCGCTGAATGTGAT
CAAAAAAGGACTGAGACATGACTGA
ATGGACGCACTATTCATCGAACTTTCCAGCTTCCAGAAATACCGGGCTGATTATCTGAATGATGATCAGTACAGGCTGTT
TCAGAACATGTTGCTGGCTGACCCTGAGAAGGGCGATGTGATACCCGATACCGGCGGACTGCGTAAAGTTCGCTTCAGGG
ATGAGCGCCGACACAAGGGCGCACGTGGCGGGATCAGGGTTATCTATTACTGGACCAACACACAAGGCCAATTCATCCTG
TTTACCATCTACGATAAAGATCAACGCGACGATTTGACCAGGCAACAGCGTGATGCCCTGGCGACCGCGCTGAATGTGAT
CAAAAAAGGACTGAGACATGACTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 12022.84 Da Isoelectric Point: 9.8806
>AT65401 WP_069026836.1 NZ_CP016890:c405190-404876 [Pantoea agglomerans]
MTERDIFSELMTGMQELKDHQEGKITLKSYKVTKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRARP
NAQAVLLIRMVQQNPETLKTLAKL
MTERDIFSELMTGMQELKDHQEGKITLKSYKVTKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRARP
NAQAVLLIRMVQQNPETLKTLAKL
Download Length: 315 bp
>AT65401 NZ_CP016890:c405190-404876 [Pantoea agglomerans]
ATGACTGAACGCGATATCTTCAGTGAACTGATGACGGGTATGCAGGAGCTTAAGGATCATCAGGAGGGCAAAATTACGCT
TAAGAGTTATAAGGTCACTAAGCGTGCCCCTGTAACTATTGCGCCGCAGGAGTTACGCGACGTACGCGAAAAACTGAACC
TCTCACAGGCCGTATTCGCCCATTATCTTCATACTGGCGAAACGACATATCAAAACTGGGAACAGGGCAGGGCGAGACCT
AACGCCCAGGCTGTTTTACTGATCCGCATGGTGCAGCAGAACCCAGAAACGCTGAAGACGCTCGCGAAGCTCTGA
ATGACTGAACGCGATATCTTCAGTGAACTGATGACGGGTATGCAGGAGCTTAAGGATCATCAGGAGGGCAAAATTACGCT
TAAGAGTTATAAGGTCACTAAGCGTGCCCCTGTAACTATTGCGCCGCAGGAGTTACGCGACGTACGCGAAAAACTGAACC
TCTCACAGGCCGTATTCGCCCATTATCTTCATACTGGCGAAACGACATATCAAAACTGGGAACAGGGCAGGGCGAGACCT
AACGCCCAGGCTGTTTTACTGATCCGCATGGTGCAGCAGAACCCAGAAACGCTGAAGACGCTCGCGAAGCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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