65395

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 47028..48358 Replicon chromosome
Accession NZ_CP016889
Organism Pantoea agglomerans strain C410P1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag BEE12_RS00215 Protein ID WP_069025151.1
Coordinates 47336..48358 (+) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag BEE12_RS00210 Protein ID WP_031591302.1
Coordinates 47028..47339 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEE12_RS00185 42493..43875 + 1383 WP_031591298.1 FAD-binding protein -
BEE12_RS00190 43888..44718 + 831 WP_069025149.1 glycosyltransferase family 8 protein -
BEE12_RS00195 44809..45930 - 1122 WP_069025150.1 Gfo/Idh/MocA family oxidoreductase -
BEE12_RS00205 46708..47043 + 336 WP_039389444.1 helix-turn-helix transcriptional regulator -
BEE12_RS00210 47028..47339 + 312 WP_031591302.1 HipA N-terminal domain-containing protein Antitoxin
BEE12_RS00215 47336..48358 + 1023 WP_069025151.1 HipA domain-containing protein Toxin
BEE12_RS00220 48484..50661 - 2178 WP_155763581.1 catalase/peroxidase HPI -
BEE12_RS00230 51189..52211 - 1023 WP_010247994.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38689.31 Da        Isoelectric Point: 6.6647

>T65395 WP_069025151.1 NZ_CP016889:47336-48358 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRMEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPDELAFVIKRYDRTASDNARLHQEQLDGAMN
LGDKYGRIDNHKAISYEKAAKFLNTRMSSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISLVP
YPAAFGEYLALPLLEREENDAGNAPGMNSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTEI

Download         Length: 1023 bp

>T65395 NZ_CP016889:47336-48358 [Pantoea agglomerans]
ATGAATTCTGAACGCTGCCTGATTACGTTAAAACGTCTTAAAGAATCTGAGCTAAAAACCGGCTACTCAACAAAAGGCAT
CCGGCATCTGCTGGGCAGTCTGAATGTGGCTCTTAGCCTGCCTTTTACGCGCAGTCAGTTTATTCAGGAACTCCCTGAAC
GTCAGAAAGGAATGAGCATTTCAGGCTATCAACCCAAACTGTCGCTTCGCATGGAAAAGGGAGAGCTGGTGGTCGTCAGC
AATGACGGCACCTATATCCTGAAACCCTCTCCGGAAGAATATCCGCACCTGGCAGAAAACGAGCATGCCACTATGTGCGT
TATGCAGCGTCTGAAATTTGACGTCCCCCCGTTCGGGCTGATGCCATTCAGACACGATGAAAATCGGCCAGACGAACTGG
CGTTTGTCATTAAAAGGTATGACCGAACAGCGTCAGATAACGCGAGATTACATCAGGAACAGCTGGATGGCGCGATGAAT
CTCGGCGATAAATATGGCAGGATTGATAATCATAAAGCCATCAGTTATGAGAAAGCCGCTAAATTCCTGAATACCAGAAT
GAGCAGCAGTTTAAAGAGTAAACGTGACCTCTTTTTGCGCATCGTGTATGCCTATGTGCTGGGAAACAATGATTTTCATC
TGCGCAATATCGGGATTATCCTGCCTCCGCAGGGTTCACCCTGGCTGGCACCGGTTTATGACTTTATCAGCCTTGTGCCC
TACCCTGCAGCGTTTGGAGAGTATTTAGCTTTGCCCCTGCTGGAACGCGAAGAAAATGATGCAGGAAACGCACCTGGGAT
GAATTCAGAGTACGGAGAATATCTGGGTGCAGACTTTATCCTGCTTGCCCAGGGTATGGATATTAATCCGACACTGGCAC
GAAAATGGCTTTCCGAGGTGGTGAGTCATCATCAGCTTATTATCGATACTTATAATGAAAGTCATATGCCTGAATCGCAG
CGGGAAGCCGTACTTGACTACGTGGCCCGAAGAATCACGTTACTGGCAGTGACCGAAATTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11696.49 Da        Isoelectric Point: 4.7953

>AT65395 WP_031591302.1 NZ_CP016889:47028-47339 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGQNGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp

>AT65395 NZ_CP016889:47028-47339 [Pantoea agglomerans]
ATGGCTCGAAAAATAGAGGTGTGGCTTTACAACACGCTGGCAGGAACGCTGAGTGAAGGGCAAAACGGTTATACTTTCTG
CTACCTGCCCACTTATGTCGGCTGTGCGATATCTCTCAGCATGCCGGTAAGACCTGAGCCCTATTTAAGTGAAGAGCTGC
ACCCCTTCTTCAAAGGTTTAGCGCCGGAAGGCTGGTTGCGAAAACGCTATTCTGAAATTCAAAAAATTGATGATAAAGAT
CTGTTCGGCTTACTGATGGAAAATGGTAACGATTTGCTTGGGGCAGTCGTCTTTAAAGAGATAACATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References