Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 31658..32318 Replicon chromosome
Accession NZ_CP016889
Organism Pantoea agglomerans strain C410P1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BEE12_RS00140 Protein ID WP_069025145.1
Coordinates 31965..32318 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BEE12_RS00135 Protein ID WP_010247918.1
Coordinates 31658..31960 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEE12_RS00115 27497..28522 - 1026 WP_208863854.1 ABC transporter permease -
BEE12_RS00120 28546..30030 - 1485 WP_069025144.1 sugar ABC transporter ATP-binding protein -
BEE12_RS00125 30063..30986 - 924 WP_010247907.1 sugar ABC transporter substrate-binding protein -
BEE12_RS00135 31658..31960 - 303 WP_010247918.1 XRE family transcriptional regulator Antitoxin
BEE12_RS00140 31965..32318 - 354 WP_069025145.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BEE12_RS00145 32617..33705 - 1089 WP_029519619.1 hypothetical protein -
BEE12_RS00150 34101..36263 + 2163 WP_081325906.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
BEE12_RS00155 36391..36663 - 273 WP_069025146.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(18-89)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13677.77 Da        Isoelectric Point: 9.1083

>T65394 WP_069025145.1 NZ_CP016889:c32318-31965 [Pantoea agglomerans]
VWMIKTTERFDRWFTLLNESDRACVLAALMVLREKGPGLSRPYADTLKGSVYINMKELRIQSRGDPIRAFFAFDPNRTAI
VLCAGNKVGNEKRFYREMLPVADREFTHWLNSFKDEE

Download         Length: 354 bp

>T65394 NZ_CP016889:c32318-31965 [Pantoea agglomerans]
GTGTGGATGATTAAAACGACGGAGAGGTTTGATCGCTGGTTTACCTTGCTTAATGAGAGCGATCGCGCCTGCGTACTGGC
AGCATTAATGGTGTTGCGCGAAAAAGGGCCGGGGTTGTCCAGGCCATACGCGGATACGTTAAAAGGCTCTGTTTATATCA
ACATGAAAGAGCTGCGTATTCAGAGTCGCGGTGATCCGATAAGGGCTTTCTTTGCTTTTGACCCAAACCGAACGGCGATT
GTGCTTTGTGCCGGAAATAAGGTGGGCAATGAAAAGCGTTTTTATCGGGAGATGCTTCCGGTTGCCGATCGGGAATTTAC
ACACTGGCTGAATAGTTTTAAAGATGAGGAGTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10941.72 Da        Isoelectric Point: 5.7251

>AT65394 WP_010247918.1 NZ_CP016889:c31960-31658 [Pantoea agglomerans]
MGRTLEQLIADEKPEVVADAQAMATDILLNIHLAELREKVQKTQVEMAKALGITQPTVAGMEKPGRDLKLSTLKRYIDAA
GGKLRLVVELPDGSHYGFEV

Download         Length: 303 bp

>AT65394 NZ_CP016889:c31960-31658 [Pantoea agglomerans]
ATGGGCAGAACGCTGGAACAGCTTATTGCGGATGAAAAACCGGAAGTCGTTGCCGACGCACAGGCGATGGCGACGGATAT
CCTGCTCAACATTCACCTTGCCGAGCTGCGTGAGAAAGTGCAGAAAACACAGGTCGAAATGGCAAAGGCGCTGGGCATTA
CACAGCCTACCGTGGCGGGCATGGAGAAGCCGGGCCGCGACCTGAAGCTCTCCACCCTCAAGCGCTATATCGATGCGGCA
GGGGGTAAGCTGCGGCTGGTGGTGGAACTGCCGGACGGCTCGCACTACGGGTTTGAGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References