Detailed information of TA system TA065305

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1019339..1019521
• Replicon: chromosome
• Accession: NZ_CP016863
• Organism: Staphylococcus aureus strain 1625.C01

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7Q05_RS15305
• Protein ID: WP_001801861.1
• Coordinates: 1019426..1019521 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1019339..1019398 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7Q05_RS05805	1018477..1018854	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
A7Q05_RS05810	1019048..1019224	+	177	Protein_1018	transposase	-
A7Q05_RS05815	1019202..1019303	-	102	WP_001791893.1	hypothetical protein	-
-	1019339..1019398	+	60	-	-	Antitoxin
A7Q05_RS15305	1019426..1019521	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7Q05_RS05825	1019724..1019867	+	144	WP_001549059.1	transposase	-
A7Q05_RS05835	1020471..1020854	+	384	WP_000070811.1	hypothetical protein	-
A7Q05_RS05840	1020865..1021041	+	177	WP_000375476.1	hypothetical protein	-
A7Q05_RS05845	1021043..1021228	+	186	WP_000809857.1	hypothetical protein	-
A7Q05_RS05850	1021342..1021983	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
A7Q05_RS05855	1022201..1022752	-	552	WP_000414205.1	hypothetical protein	-
A7Q05_RS05860	1022850..1023194	-	345	WP_000627551.1	DUF3969 family protein	-
A7Q05_RS05865	1023235..1023861	-	627	Protein_1028	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	986250..1045560	59310

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T65305 WP_001801861.1 NZ_CP016863:c1019521-1019426 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T65305 NZ_CP016863:c1019521-1019426 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT65305 NZ_CP016863:1019339-1019398 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin