Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 683707..683970 Replicon chromosome
Accession NZ_CP016863
Organism Staphylococcus aureus strain 1625.C01

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag A7Q05_RS03730 Protein ID WP_001802298.1
Coordinates 683707..683811 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 683806..683970 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7Q05_RS03705 679091..679873 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
A7Q05_RS03710 679941..680798 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
A7Q05_RS03715 681503..681595 - 93 WP_001790138.1 hypothetical protein -
A7Q05_RS03720 681884..683020 + 1137 WP_000115564.1 SAP domain-containing protein -
A7Q05_RS15300 683063..683546 + 484 Protein_667 recombinase family protein -
A7Q05_RS03730 683707..683811 + 105 WP_001802298.1 hypothetical protein Toxin
- 683806..683970 - 165 - - Antitoxin
A7Q05_RS03735 684311..685402 - 1092 WP_000495671.1 lytic regulatory protein -
A7Q05_RS03740 685668..686648 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
A7Q05_RS03745 686650..686970 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
A7Q05_RS03750 687122..687787 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T65295 WP_001802298.1 NZ_CP016863:683707-683811 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T65295 NZ_CP016863:683707-683811 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT65295 NZ_CP016863:c683970-683806 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References