Detailed information of TA system TA065289

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2314760..2314942
• Replicon: chromosome
• Accession: NZ_CP016861
• Organism: Staphylococcus aureus strain 1969.N

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7U52_RS15415
• Protein ID: WP_001801861.1
• Coordinates: 2314847..2314942 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2314760..2314819 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7U52_RS12570	2313898..2314275	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
A7U52_RS12575	2314469..2314645	+	177	Protein_2251	transposase	-
A7U52_RS12580	2314623..2314724	-	102	WP_001791893.1	hypothetical protein	-
-	2314760..2314819	+	60	-	-	Antitoxin
A7U52_RS15415	2314847..2314942	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7U52_RS12590	2315145..2315288	+	144	WP_001549059.1	transposase	-
A7U52_RS12600	2315892..2316275	+	384	WP_000070811.1	hypothetical protein	-
A7U52_RS12605	2316286..2316462	+	177	WP_000375476.1	hypothetical protein	-
A7U52_RS12610	2316464..2316649	+	186	WP_000809857.1	hypothetical protein	-
A7U52_RS12615	2316763..2317404	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
A7U52_RS12620	2317622..2318173	-	552	WP_000414205.1	hypothetical protein	-
A7U52_RS12625	2318271..2318615	-	345	WP_000627551.1	DUF3969 family protein	-
A7U52_RS12630	2318656..2319282	-	627	Protein_2261	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	2281671..2352395	70724

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T65289 WP_001801861.1 NZ_CP016861:c2314942-2314847 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T65289 NZ_CP016861:c2314942-2314847 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT65289 NZ_CP016861:2314760-2314819 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin