65280

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1979069..1979348 Replicon chromosome
Accession NZ_CP016861
Organism Staphylococcus aureus strain 1969.N

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag A7U52_RS10495 Protein ID WP_001802298.1
Coordinates 1979069..1979173 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1979169..1979348 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7U52_RS10470 1974453..1975235 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
A7U52_RS10475 1975303..1976160 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
A7U52_RS10480 1976865..1976957 - 93 WP_001790138.1 hypothetical protein -
A7U52_RS10485 1977246..1978382 + 1137 WP_000115564.1 SAP domain-containing protein -
A7U52_RS15410 1978425..1978908 + 484 Protein_1901 recombinase family protein -
A7U52_RS10495 1979069..1979173 + 105 WP_001802298.1 hypothetical protein Toxin
- 1979169..1979348 - 180 - - Antitoxin
A7U52_RS10500 1979673..1980764 - 1092 WP_000495671.1 lytic regulatory protein -
A7U52_RS10505 1981030..1982010 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
A7U52_RS10510 1982012..1982332 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
A7U52_RS10515 1982484..1983149 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T65280 WP_001802298.1 NZ_CP016861:1979069-1979173 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T65280 NZ_CP016861:1979069-1979173 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
CAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT65280 NZ_CP016861:c1979348-1979169 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References