Detailed information of TA system TA065272

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2323628..2323810
• Replicon: chromosome
• Accession: NZ_CP016858
• Organism: Staphylococcus aureus strain 1971.C01

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7U47_RS15475
• Protein ID: WP_001801861.1
• Coordinates: 2323715..2323810 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2323628..2323687 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7U47_RS12560	2322766..2323143	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
A7U47_RS12565	2323337..2323513	+	177	Protein_2274	transposase	-
A7U47_RS12570	2323491..2323592	-	102	WP_001791893.1	hypothetical protein	-
-	2323628..2323687	+	60	-	-	Antitoxin
A7U47_RS15475	2323715..2323810	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7U47_RS12580	2324013..2324156	+	144	WP_001549059.1	transposase	-
A7U47_RS12590	2324760..2325143	+	384	WP_000070811.1	hypothetical protein	-
A7U47_RS12595	2325154..2325330	+	177	WP_000375476.1	hypothetical protein	-
A7U47_RS12600	2325332..2325517	+	186	WP_000809857.1	hypothetical protein	-
A7U47_RS12605	2325631..2326272	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
A7U47_RS12610	2326490..2327041	-	552	WP_000414205.1	hypothetical protein	-
A7U47_RS12615	2327139..2327483	-	345	WP_000627551.1	DUF3969 family protein	-
A7U47_RS12620	2327524..2328150	-	627	Protein_2284	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	2290539..2361263	70724

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T65272 WP_001801861.1 NZ_CP016858:c2323810-2323715 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T65272 NZ_CP016858:c2323810-2323715 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT65272 NZ_CP016858:2323628-2323687 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin