Detailed information of TA system TA065255

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2308766..2308946
• Replicon: chromosome
• Accession: NZ_CP016856
• Organism: Staphylococcus aureus strain 2148.N

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7U44_RS14220
• Protein ID: WP_001801861.1
• Coordinates: 2308851..2308946 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2308766..2308823 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7U44_RS12025	2305117..2306235	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
A7U44_RS12030	2306883..2307299	+	417	WP_020978241.1	DUF1433 domain-containing protein	-
A7U44_RS12035	2307536..2307883	+	348	WP_001566695.1	DUF1433 domain-containing protein	-
A7U44_RS12040	2307905..2308279	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
A7U44_RS12045	2308467..2308649	+	183	Protein_2219	transposase	-
A7U44_RS12050	2308627..2308728	-	102	WP_001791232.1	hypothetical protein	-
-	2308766..2308823	+	58	-	-	Antitoxin
A7U44_RS14220	2308851..2308946	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7U44_RS12060	2309397..2309843	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
A7U44_RS12065	2310528..2310911	+	384	WP_000070811.1	hypothetical protein	-
A7U44_RS12070	2310922..2311098	+	177	WP_000375476.1	hypothetical protein	-
A7U44_RS12080	2311469..2312026	+	558	WP_103672653.1	ImmA/IrrE family metallo-endopeptidase	-
A7U44_RS12085	2312224..2312796	-	573	WP_000414206.1	hypothetical protein	-
A7U44_RS12090	2312897..2313238	-	342	WP_000627547.1	DUF3969 family protein	-
A7U44_RS12095	2313279..2313905	-	627	WP_000669021.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	2279870..2316463	36593

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T65255 WP_001801861.1 NZ_CP016856:c2308946-2308851 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T65255 NZ_CP016856:c2308946-2308851 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT65255 NZ_CP016856:2308766-2308823 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin