Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1972877..1973155 Replicon chromosome
Accession NZ_CP016856
Organism Staphylococcus aureus strain 2148.N

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag A7U44_RS09995 Protein ID WP_001802298.1
Coordinates 1972877..1972981 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1972977..1973155 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7U44_RS09970 1969674..1970456 + 783 WP_000908189.1 ABC transporter ATP-binding protein -
A7U44_RS09975 1970524..1971381 + 858 WP_000370928.1 Cof-type HAD-IIB family hydrolase -
A7U44_RS09985 1972039..1972197 - 159 WP_001792784.1 hypothetical protein -
A7U44_RS14245 1972190..1972360 - 171 WP_001792292.1 transposase -
A7U44_RS09995 1972877..1972981 + 105 WP_001802298.1 hypothetical protein Toxin
- 1972977..1973155 - 179 - - Antitoxin
A7U44_RS10000 1973480..1974571 - 1092 WP_000495681.1 hypothetical protein -
A7U44_RS10005 1974837..1975817 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
A7U44_RS10010 1975819..1976139 - 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
A7U44_RS10015 1976291..1976956 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T65246 WP_001802298.1 NZ_CP016856:1972877-1972981 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T65246 NZ_CP016856:1972877-1972981 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT65246 NZ_CP016856:c1973155-1972977 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References