Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2679260..2679539 Replicon chromosome
Accession NZ_CP016855
Organism Staphylococcus aureus strain 5118.N

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag A7U51_RS14185 Protein ID WP_001802298.1
Coordinates 2679260..2679364 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2679360..2679539 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7U51_RS14160 2674644..2675426 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
A7U51_RS14165 2675494..2676351 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
A7U51_RS14170 2677056..2677148 - 93 WP_001790138.1 hypothetical protein -
A7U51_RS14175 2677437..2678573 + 1137 WP_000115564.1 SAP domain-containing protein -
A7U51_RS15415 2678616..2679099 + 484 Protein_2578 recombinase family protein -
A7U51_RS14185 2679260..2679364 + 105 WP_001802298.1 hypothetical protein Toxin
- 2679360..2679539 - 180 - - Antitoxin
A7U51_RS14190 2679864..2680955 - 1092 WP_000495671.1 lytic regulatory protein -
A7U51_RS14195 2681221..2682201 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
A7U51_RS14200 2682203..2682523 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
A7U51_RS14205 2682675..2683340 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T65232 WP_001802298.1 NZ_CP016855:2679260-2679364 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T65232 NZ_CP016855:2679260-2679364 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT65232 NZ_CP016855:c2679539-2679360 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References