Detailed information of TA system TA065224

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 185246..185428
• Replicon: chromosome
• Accession: NZ_CP016855
• Organism: Staphylococcus aureus strain 5118.N

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7U51_RS01530
• Protein ID: WP_001801861.1
• Coordinates: 185333..185428 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	185246..185305 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7U51_RS01515	184384..184761	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
A7U51_RS01520	184955..185131	+	177	Protein_198	transposase	-
A7U51_RS01525	185109..185210	-	102	WP_001791893.1	hypothetical protein	-
-	185246..185305	+	60	-	-	Antitoxin
A7U51_RS01530	185333..185428	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7U51_RS01540	185631..185774	+	144	WP_001549059.1	transposase	-
A7U51_RS01550	186378..186761	+	384	WP_000070811.1	hypothetical protein	-
A7U51_RS01555	186772..186948	+	177	WP_000375476.1	hypothetical protein	-
A7U51_RS01560	186950..187135	+	186	WP_000809857.1	hypothetical protein	-
A7U51_RS01565	187249..187890	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
A7U51_RS01570	188108..188659	-	552	WP_000414205.1	hypothetical protein	-
A7U51_RS01575	188757..189101	-	345	WP_000627551.1	DUF3969 family protein	-
A7U51_RS01580	189142..189768	-	627	Protein_208	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	152156..222881	70725

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T65224 WP_001801861.1 NZ_CP016855:c185428-185333 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T65224 NZ_CP016855:c185428-185333 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT65224 NZ_CP016855:185246-185305 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin