Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 55320..55825 Replicon plasmid pL21581-2
Accession NZ_CP016846
Organism Carnobacterium maltaromaticum strain TMW 2.1581

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1X6WJQ1
Locus tag BFC23_RS16760 Protein ID WP_022797157.1
Coordinates 55559..55825 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID U5SCD4
Locus tag BFC23_RS16755 Protein ID WP_010620828.1
Coordinates 55320..55574 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFC23_RS16725 51659..51892 - 234 WP_003103602.1 cation transporter -
BFC23_RS16730 52039..52686 - 648 WP_034558129.1 prolipoprotein diacylglyceryl transferase -
BFC23_RS16735 52671..53009 - 339 WP_002300938.1 hypothetical protein -
BFC23_RS16745 53238..53942 - 705 WP_002293764.1 Crp/Fnr family transcriptional regulator -
BFC23_RS16750 54087..54659 - 573 WP_002292150.1 DNA starvation/stationary phase protection protein -
BFC23_RS16755 55320..55574 + 255 WP_010620828.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BFC23_RS16760 55559..55825 + 267 WP_022797157.1 Txe/YoeB family addiction module toxin Toxin
BFC23_RS16765 56218..56538 + 321 WP_087064520.1 plasmid mobilization relaxosome protein MobC -
BFC23_RS16770 56711..59716 - 3006 WP_119907126.1 Tn3 family transposase -
BFC23_RS16775 59901..60485 + 585 WP_119907127.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81683 81683


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-62)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10465.06 Da        Isoelectric Point: 9.8673

>T65191 WP_022797157.1 NZ_CP016846:55559-55825 [Carnobacterium maltaromaticum]
MGYSIKLAKSTMKDLKNLKSAHLEQKFKDIMEILKENPFQNPPPYEKLVGNLKDNYSRRLNIQHRVVYSVDNDAKEVIIW
SAWTHYER

Download         Length: 267 bp

>T65191 NZ_CP016846:55559-55825 [Carnobacterium maltaromaticum]
TTGGGATACTCTATAAAGTTAGCAAAATCAACAATGAAAGACCTTAAAAATTTAAAATCGGCTCATTTAGAGCAAAAATT
TAAAGATATAATGGAAATTTTAAAAGAGAACCCGTTTCAAAATCCACCGCCTTATGAGAAGCTAGTCGGAAATTTAAAAG
ATAACTATTCCCGACGATTAAATATTCAACACCGAGTGGTTTACTCGGTTGATAATGACGCAAAAGAAGTCATTATTTGG
TCGGCTTGGACGCACTACGAAAGATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9673.80 Da        Isoelectric Point: 4.1473

>AT65191 WP_010620828.1 NZ_CP016846:55320-55574 [Carnobacterium maltaromaticum]
MSIVNPSQARKVFYQLLKDVNKTNEPIYISGKNEESEAVMVSKKDWDAIQETLYLQSAGVADVIHQREQENEFVALEDID
WDTL

Download         Length: 255 bp

>AT65191 NZ_CP016846:55320-55574 [Carnobacterium maltaromaticum]
ATGTCTATCGTAAACCCTAGCCAAGCTAGAAAAGTCTTTTATCAACTATTGAAAGACGTCAATAAAACTAACGAACCCAT
TTATATCTCTGGCAAAAACGAAGAAAGTGAAGCCGTTATGGTCAGTAAAAAAGACTGGGACGCAATTCAAGAAACATTAT
ACCTTCAATCTGCTGGCGTAGCAGATGTGATCCACCAGCGTGAACAAGAAAATGAGTTTGTTGCATTGGAGGATATCGAT
TGGGATACTCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X6WJQ1

Antitoxin

Source ID Structure
AlphaFold DB A0A1H6W4Y2

References