Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1440783..1441483 Replicon chromosome
Accession NZ_CP016449
Organism Hydrogenophaga sp. RAC07

Toxin (Protein)


Gene name mqsR Uniprot ID A0A1B3LSW0
Locus tag BSY239_RS06745 Protein ID WP_069046170.1
Coordinates 1441187..1441483 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A1B3M3U5
Locus tag BSY239_RS06740 Protein ID WP_069046169.1
Coordinates 1440783..1441184 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY239_RS06730 1436189..1437490 + 1302 WP_069046167.1 DNA polymerase Y family protein -
BSY239_RS06735 1437606..1440758 + 3153 WP_069046168.1 error-prone DNA polymerase -
BSY239_RS06740 1440783..1441184 - 402 WP_069046169.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
BSY239_RS06745 1441187..1441483 - 297 WP_069046170.1 type II toxin-antitoxin system MqsR family toxin Toxin
BSY239_RS06750 1441579..1442061 - 483 WP_069046171.1 EVE domain-containing protein -
BSY239_RS06755 1442104..1443873 - 1770 WP_069046172.1 HAMP domain-containing protein -
BSY239_RS06760 1443947..1444483 - 537 WP_083240166.1 chemotaxis protein CheW -
BSY239_RS06765 1444626..1445597 + 972 WP_069048837.1 NAD(P)H-binding protein -
BSY239_RS06770 1445670..1446083 - 414 WP_069046173.1 DUF4148 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10698.42 Da        Isoelectric Point: 8.1028

>T64645 WP_069046170.1 NZ_CP016449:c1441483-1441187 [Hydrogenophaga sp. RAC07]
MEKGKPHCKLQTVKTLVASGHVRSTFSALAGGAALGLDFDGIVAVVMSLTSKDFHKSMTTHADHRIWQDVYRPSTPVGDL
YLKLTVVDDVLIVSFKEL

Download         Length: 297 bp

>T64645 NZ_CP016449:c1441483-1441187 [Hydrogenophaga sp. RAC07]
ATGGAAAAAGGCAAGCCGCACTGCAAGTTGCAGACGGTCAAGACGCTGGTTGCATCCGGTCATGTGAGATCCACGTTCTC
TGCGCTGGCCGGTGGTGCGGCGCTGGGGCTGGATTTCGACGGCATCGTGGCGGTGGTGATGTCGCTGACATCAAAGGACT
TCCACAAAAGCATGACCACGCATGCCGACCACCGCATCTGGCAAGACGTGTACCGCCCGTCAACCCCGGTGGGCGATCTC
TATCTGAAACTCACCGTCGTTGACGACGTGCTCATCGTGTCATTCAAGGAGCTCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14488.68 Da        Isoelectric Point: 7.1892

>AT64645 WP_069046169.1 NZ_CP016449:c1441184-1440783 [Hydrogenophaga sp. RAC07]
MKCPHCGAAKLVHDTRDMSYTYKGESTTIPAVSGDFCPSCDEVVLNAAESARLSAAMLDFNKQVNAAIVDPAFIVNVRKK
LALDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLRVLDRHPELLDEVRAV

Download         Length: 402 bp

>AT64645 NZ_CP016449:c1441184-1440783 [Hydrogenophaga sp. RAC07]
ATGAAATGCCCTCACTGTGGTGCCGCGAAGCTGGTGCACGACACCCGCGACATGTCCTACACCTACAAGGGCGAAAGCAC
CACCATCCCCGCCGTCTCGGGCGACTTCTGCCCTTCGTGTGACGAGGTTGTTCTCAATGCTGCCGAATCCGCCCGACTGA
GCGCGGCGATGCTGGATTTCAACAAACAGGTGAACGCCGCCATCGTGGATCCGGCCTTCATCGTCAACGTGCGCAAGAAG
CTCGCACTGGACCAGCGCGAAGCCGCCGAGATTTTTGGCGGTGGGGTCAACGCGTTCTCCCGCTACGAGAACGGCAAGAC
CAAGCCACCGCTGGCGCTGGTGAAACTGCTCAGGGTGCTGGACCGGCATCCGGAATTGCTGGATGAGGTGCGCGCTGTCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B3LSW0

Antitoxin

Source ID Structure
AlphaFold DB A0A1B3M3U5

References