Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 657125..657825 Replicon chromosome
Accession NZ_CP016443
Organism Burkholderia stabilis strain ATCC BAA-67

Toxin (Protein)


Gene name mqsR Uniprot ID A0A1D7ZJL7
Locus tag BBJ41_RS20980 Protein ID WP_069748245.1
Coordinates 657125..657421 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A1D7ZJM1
Locus tag BBJ41_RS20985 Protein ID WP_069748246.1
Coordinates 657424..657825 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BBJ41_RS20965 653643..655193 + 1551 WP_069748242.1 sensor domain-containing diguanylate cyclase -
BBJ41_RS20970 655455..655730 + 276 WP_069748243.1 hypothetical protein -
BBJ41_RS20975 655984..657018 + 1035 WP_069748244.1 succinylglutamate desuccinylase/aspartoacylase family protein -
BBJ41_RS20980 657125..657421 + 297 WP_069748245.1 type II toxin-antitoxin system MqsR family toxin Toxin
BBJ41_RS20985 657424..657825 + 402 WP_069748246.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
BBJ41_RS20990 658134..658694 + 561 WP_069748247.1 GNAT family N-acetyltransferase -
BBJ41_RS20995 658745..659692 + 948 WP_069748248.1 ABC transporter substrate-binding protein -
BBJ41_RS21000 659743..660792 + 1050 WP_069748249.1 LLM class flavin-dependent oxidoreductase -
BBJ41_RS21005 660800..662152 + 1353 WP_069748250.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11170.86 Da        Isoelectric Point: 8.0534

>T64633 WP_069748245.1 NZ_CP016443:657125-657421 [Burkholderia stabilis]
MEKNTPHCKLSRVRTLVEIGKVRLTASAVFGARQLGFTEQEAIDVVVSLTAVDFHKSMTTYADHTIWQDVYQRRTVNGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T64633 NZ_CP016443:657125-657421 [Burkholderia stabilis]
ATGGAAAAGAACACGCCTCATTGCAAGCTGTCCCGAGTCAGAACACTCGTCGAGATCGGCAAGGTGCGTTTGACCGCGAG
CGCAGTATTCGGCGCCCGGCAACTCGGTTTTACGGAGCAGGAGGCGATCGATGTCGTCGTGTCGCTGACAGCCGTCGATT
TCCACAAGAGCATGACGACGTATGCCGATCACACGATCTGGCAAGACGTCTATCAGCGTCGCACCGTGAACGGCGACGTG
TACCTGAAACTCACCGTGATCGACGATGTGCTGATCGTGTCTTTCAAGGAGCGTTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14629.92 Da        Isoelectric Point: 8.1146

>AT64633 WP_069748246.1 NZ_CP016443:657424-657825 [Burkholderia stabilis]
MKCPACGAAKLVRDTRDIPYTYKGRSTVVPDITGDFCPACGESVLDLDEATRLGEAITEFNKQVNSTIVDPKFIAKVRKK
LMLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLFKILDRHPDLLTEVRAA

Download         Length: 402 bp

>AT64633 NZ_CP016443:657424-657825 [Burkholderia stabilis]
ATGAAGTGCCCAGCATGCGGCGCCGCCAAACTGGTTCGCGATACCCGCGACATTCCCTATACGTACAAGGGTCGATCGAC
CGTCGTCCCCGATATCACCGGTGATTTCTGTCCGGCCTGCGGAGAATCGGTCCTTGACCTCGACGAGGCAACGCGTCTCG
GCGAAGCGATCACCGAGTTCAACAAACAGGTGAACTCAACCATCGTCGACCCGAAGTTCATTGCGAAGGTCCGCAAGAAG
CTGATGCTGGATCAGCGCGAGGCGGCCGAAATATTCGGTGGCGGCGTCAACGCATTTTCTCGCTACGAAACGGGCAAGAC
GAACCCGCCGCTTGCCCTTGTGAAGCTGTTCAAAATCCTGGATCGCCATCCGGATCTGCTCACAGAAGTGCGGGCCGCAT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7ZJL7

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7ZJM1

References