Detailed information of TA system TA064557

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1826998..1827178
• Replicon: chromosome
• Accession: NZ_CP016398
• Organism: Staphylococcus aureus strain FORC_040

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FORC40_RS14265
• Protein ID: WP_001801861.1
• Coordinates: 1826998..1827093 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1827121..1827178 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC40_RS08995	1822039..1822665	+	627	WP_000669021.1	hypothetical protein	-
FORC40_RS09000	1822706..1823047	+	342	WP_000627547.1	DUF3969 family protein	-
FORC40_RS09005	1823148..1823720	+	573	WP_000414206.1	hypothetical protein	-
FORC40_RS09010	1823918..1824475	-	558	WP_000864139.1	ImmA/IrrE family metallo-endopeptidase	-
FORC40_RS09020	1824846..1825022	-	177	WP_000375476.1	hypothetical protein	-
FORC40_RS09025	1825033..1825416	-	384	WP_000070811.1	hypothetical protein	-
FORC40_RS09030	1826101..1826547	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
FORC40_RS14265	1826998..1827093	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1827121..1827178	-	58	-	-	Antitoxin
FORC40_RS09040	1827216..1827317	+	102	WP_001791232.1	hypothetical protein	-
FORC40_RS09045	1827295..1827477	-	183	Protein_1699	transposase	-
FORC40_RS09050	1827665..1828039	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
FORC40_RS09055	1828061..1828408	-	348	WP_001566695.1	DUF1433 domain-containing protein	-
FORC40_RS09060	1828645..1829061	-	417	WP_020978241.1	DUF1433 domain-containing protein	-
FORC40_RS09065	1829708..1830826	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1797464..1854329	56865
	-	inside	Prophage	-	lukD / hlgA / selk	1801182..1856997	55815

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T64557 WP_001801861.1 NZ_CP016398:1826998-1827093 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T64557 NZ_CP016398:1826998-1827093 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT64557 NZ_CP016398:c1827178-1827121 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin