Detailed information of TA system TA064512

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 2397131..2397353
• Replicon: chromosome
• Accession: NZ_CP016358
• Organism: Escherichia coli strain K-15KW01

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: BA058_RS27345
• Protein ID: WP_001295224.1
• Coordinates: 2397131..2397238 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	2397287..2397353 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BA058_RS11600	2392384..2393136	-	753	WP_000279536.1	cellulose biosynthesis protein BcsQ	-
BA058_RS11605	2393148..2393336	-	189	WP_001063314.1	YhjR family protein	-
BA058_RS11610	2393609..2395180	+	1572	WP_001204945.1	cellulose biosynthesis protein BcsE	-
BA058_RS11615	2395177..2395368	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
BA058_RS11620	2395365..2397044	+	1680	WP_000191565.1	cellulose biosynthesis protein BcsG	-
BA058_RS27345	2397131..2397238	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	2397287..2397353	+	67	-	-	Antitoxin
BA058_RS11635	2397714..2398985	+	1272	WP_001298005.1	amino acid permease	-
BA058_RS11640	2399015..2400019	-	1005	WP_000103577.1	dipeptide ABC transporter ATP-binding subunit DppF	-
BA058_RS11645	2400016..2400999	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
BA058_RS11650	2401010..2401912	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T64512 WP_001295224.1 NZ_CP016358:c2397238-2397131 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T64512 NZ_CP016358:c2397238-2397131 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT64512 NZ_CP016358:2397287-2397353 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin