Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 916716..917236 Replicon chromosome
Accession NZ_CP016320
Organism Rhizobium sp. S41

Toxin (Protein)


Gene name yoeB Uniprot ID A0A098RUX8
Locus tag BA939_RS04610 Protein ID WP_037089950.1
Coordinates 916716..916985 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A098RWL5
Locus tag BA939_RS04615 Protein ID WP_037089948.1
Coordinates 916982..917236 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BA939_RS04590 911722..913416 - 1695 WP_037089954.1 iron ABC transporter permease -
BA939_RS04595 913426..914409 - 984 WP_037089952.1 ABC transporter substrate-binding protein -
BA939_RS04600 914745..915989 - 1245 WP_004442697.1 PLP-dependent aminotransferase family protein -
BA939_RS04605 916262..916711 + 450 WP_037089951.1 RbsD/FucU family protein -
BA939_RS04610 916716..916985 - 270 WP_037089950.1 Txe/YoeB family addiction module toxin Toxin
BA939_RS04615 916982..917236 - 255 WP_037089948.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BA939_RS04620 917374..918393 - 1020 WP_003495030.1 ketol-acid reductoisomerase -
BA939_RS04625 918443..919096 - 654 WP_004442706.1 TetR/AcrR family transcriptional regulator -
BA939_RS04630 919493..920398 - 906 WP_037089946.1 AraC family transcriptional regulator -
BA939_RS04635 920588..921637 + 1050 WP_037089944.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10612.09 Da        Isoelectric Point: 9.8742

>T64423 WP_037089950.1 NZ_CP016320:c916985-916716 [Rhizobium sp. S41]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRISAEHRFVYRVSGSGSEQRLE
IIQCRFHYQ

Download         Length: 270 bp

>T64423 NZ_CP016320:c916985-916716 [Rhizobium sp. S41]
ATGAAGCTCGTCTGGACGCTGAGTTCATGGGACGATTACGAGTTCTGGCAAAGAACCGATGCTCGTATGGTAGAGAAAAT
TAACGACCTCATACGGAATGCCAAACGGACGCCCTTTGCTGGGCTCGGAAAACCGGAGCCTCTGAAGGGCGATATGGCAG
GATATTGGTCTCGGCGGATTTCCGCCGAGCATCGGTTTGTCTATCGTGTATCCGGGTCCGGCAGCGAACAAAGGCTGGAG
ATCATCCAGTGCCGCTTCCATTACCAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9702.92 Da        Isoelectric Point: 4.6631

>AT64423 WP_037089948.1 NZ_CP016320:c917236-916982 [Rhizobium sp. S41]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANALRLRTSMDQLERGDIIERD
PTEE

Download         Length: 255 bp

>AT64423 NZ_CP016320:c917236-916982 [Rhizobium sp. S41]
ATGGCAAATGTGCGATTCACGGAATTCCGGCAGAACTTCGCGACCCATTTCGACCGGGTTCTGGAGACGCGCGCGCCGTT
GCTGGTTACTCGGCAGGGGAAGGAGGCGGTCGTGGTTCTCGCTGAGGGGGAATACGAGAGCATGCAGGAAACGCTGCATC
TTTTATCCAACCCGGCAAATGCCTTACGACTTCGTACTTCCATGGATCAACTTGAACGCGGCGATATCATCGAGCGGGAT
CCAACCGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A098RUX8

Antitoxin

Source ID Structure
AlphaFold DB A0A098RWL5

References