64206

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 214720..215243 Replicon chromosome
Accession NZ_CP016073
Organism Staphylococcus pseudintermedius strain 081661 isolate 20081661

Toxin (Protein)


Gene name yoeB Uniprot ID A0A317Z6J3
Locus tag A9I65_RS00930 Protein ID WP_037542127.1
Coordinates 214977..215243 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2P5PI69
Locus tag A9I65_RS00925 Protein ID WP_015729747.1
Coordinates 214720..214977 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9I65_RS00915 211867..212361 - 495 WP_037542124.1 membrane protein -
A9I65_RS00920 212621..214525 + 1905 WP_037542126.1 triacylglycerol lipase -
A9I65_RS00925 214720..214977 + 258 WP_015729747.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
A9I65_RS00930 214977..215243 + 267 WP_037542127.1 Txe/YoeB family addiction module toxin Toxin
A9I65_RS00935 215604..215705 - 102 WP_019169745.1 DUF2648 domain-containing protein -
A9I65_RS00940 215719..217212 - 1494 WP_014612817.1 malate dehydrogenase (quinone) -
A9I65_RS13655 217968..218069 + 102 Protein_191 KxYKxGKxW signal peptide domain-containing protein -
A9I65_RS13660 219844..219990 + 147 WP_157978016.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10555.10 Da        Isoelectric Point: 10.1602

>T64206 WP_037542127.1 NZ_CP016073:214977-215243 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREVYI
FSAWSYYE

Download         Length: 267 bp

>T64206 NZ_CP016073:214977-215243 [Staphylococcus pseudintermedius]
ATGGGTAATTATTCTGTCTTAATTAAGAATTCAGCCAAAAATGACTTGAAAAAAATTAAAAAGTCACTTCTTAAAGAGCA
ATTTTCAAAAATTATTGAAGTTTTAAAGATTAACCCTTATGAAGCTAGTCAATCTTTTGAGAAGCTACAACCGAAGCATT
CAGCTCGATATTCAAGGCGTCTGAATCATCAACATAGAGTTGTGTATACGGTTGATGATGAAAAAAGAGAAGTTTATATT
TTTTCTGCTTGGTCATATTATGAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9836.85 Da        Isoelectric Point: 4.1100

>AT64206 WP_015729747.1 NZ_CP016073:214720-214977 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDGIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL

Download         Length: 258 bp

>AT64206 NZ_CP016073:214720-214977 [Staphylococcus pseudintermedius]
ATGATTATTAAAACGCCTACAAATGCTAGAAAAGAGTTTTACGAGTTGTTAAAACAAGTTAATGATAATCATGAGCCTAT
TATAATAAGTGGTTCTAAAAGTGAAAACAATGCAGTTATTGTTAGTCAGGAAGACTGGGATGGTATTCAAGAAACGTTAT
TTCTCGAATACACTGGTACTATGGATAAAGTAAGAGCACGTGAAAAAGATGATAGTGGTTATACCAATATTGACGATATA
GATTGGGATAATTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A317Z6J3

Antitoxin

Source ID Structure
AlphaFold DB A0A2P5PI69

References