Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 227782..228305 | Replicon | chromosome |
Accession | NZ_CP016072 | ||
Organism | Staphylococcus pseudintermedius strain NA45 isolate UWMNA45 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A8H9EQJ3 |
Locus tag | A9I66_RS00965 | Protein ID | WP_014612815.1 |
Coordinates | 228039..228305 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A3D8YKM0 |
Locus tag | A9I66_RS00960 | Protein ID | WP_014612814.1 |
Coordinates | 227782..228039 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A9I66_RS00950 | 224930..225424 | - | 495 | WP_015729749.1 | membrane protein | - |
A9I66_RS00955 | 225684..227588 | + | 1905 | WP_065353959.1 | triacylglycerol lipase | - |
A9I66_RS00960 | 227782..228039 | + | 258 | WP_014612814.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
A9I66_RS00965 | 228039..228305 | + | 267 | WP_014612815.1 | Txe/YoeB family addiction module toxin | Toxin |
A9I66_RS00970 | 228666..228767 | - | 102 | WP_019169745.1 | DUF2648 domain-containing protein | - |
A9I66_RS00975 | 228781..230274 | - | 1494 | WP_014612817.1 | malate dehydrogenase (quinone) | - |
A9I66_RS14330 | 231031..231132 | + | 102 | Protein_198 | KxYKxGKxW signal peptide domain-containing protein | - |
A9I66_RS14335 | 232565..233014 | - | 450 | WP_201035852.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10555.15 Da Isoelectric Point: 10.2281
>T64203 WP_014612815.1 NZ_CP016072:228039-228305 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYLRRLNHQHRVVYTVDDEKREVYI
FSAWSHYE
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYLRRLNHQHRVVYTVDDEKREVYI
FSAWSHYE
Download Length: 267 bp
>T64203 NZ_CP016072:228039-228305 [Staphylococcus pseudintermedius]
ATGGGTAATTATTCTGTTTTAATTAAGAATTCAGCCAAAAATGACTTAAAAAAAATTAAAAAGTCACTTCTTAAAGAGCA
ATTTTCAAAAATTATTGAAGTTTTAAAGATTAACCCTTATGAAGCTAGTCAATCTTTTGAGAAGCTACAACCGAAGCATT
CAGCTCGATATTTAAGGCGTCTGAATCATCAACATAGAGTTGTGTATACGGTTGATGATGAAAAAAGAGAAGTTTATATT
TTTTCTGCTTGGTCACATTATGAGTGA
ATGGGTAATTATTCTGTTTTAATTAAGAATTCAGCCAAAAATGACTTAAAAAAAATTAAAAAGTCACTTCTTAAAGAGCA
ATTTTCAAAAATTATTGAAGTTTTAAAGATTAACCCTTATGAAGCTAGTCAATCTTTTGAGAAGCTACAACCGAAGCATT
CAGCTCGATATTTAAGGCGTCTGAATCATCAACATAGAGTTGTGTATACGGTTGATGATGAAAAAAGAGAAGTTTATATT
TTTTCTGCTTGGTCACATTATGAGTGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9866.87 Da Isoelectric Point: 4.1100
>AT64203 WP_014612814.1 NZ_CP016072:227782-228039 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL
Download Length: 258 bp
>AT64203 NZ_CP016072:227782-228039 [Staphylococcus pseudintermedius]
ATGATTATTAAAACGCCTACAAATGCTAGAAAAGAGTTTTACGAGTTGTTAAAACAAGTTAATGATAATCATGAGCCTAT
TATAATAAGTGGTTCTAAAAGTGAAAACAATGCAGTTATTGTTAGTCAGGAAGACTGGGATAGTATTCAAGAAACGTTAT
TTCTCGAATACACTGGTACTATGGATAAAGTAAGAGCACGTGAAAAAGATGATAGTGGTTATACCAATATTGACGATATA
GATTGGGATAATTTGTAA
ATGATTATTAAAACGCCTACAAATGCTAGAAAAGAGTTTTACGAGTTGTTAAAACAAGTTAATGATAATCATGAGCCTAT
TATAATAAGTGGTTCTAAAAGTGAAAACAATGCAGTTATTGTTAGTCAGGAAGACTGGGATAGTATTCAAGAAACGTTAT
TTCTCGAATACACTGGTACTATGGATAAAGTAAGAGCACGTGAAAAAGATGATAGTGGTTATACCAATATTGACGATATA
GATTGGGATAATTTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|