Detailed information of TA system TA063886

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 53270..53511
• Replicon: plasmid Efsorialis-p2
• Accession: NZ_CP015885
• Organism: Enterococcus faecalis strain sorialis

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: A6B47_RS15280
• Protein ID: WP_002360667.1
• Coordinates: 53270..53380 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	53420..53511 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A6B47_RS15235	48670..48984	+	315	WP_002401837.1	hypothetical protein	-
A6B47_RS15240	49187..49807	+	621	WP_002366000.1	recombinase family protein	-
A6B47_RS15245	49797..50111	+	315	WP_025190469.1	hypothetical protein	-
A6B47_RS15250	50105..50329	+	225	WP_002414746.1	hypothetical protein	-
A6B47_RS15255	50390..50599	+	210	WP_002399367.1	hypothetical protein	-
A6B47_RS15260	50611..50913	+	303	WP_002393766.1	hypothetical protein	-
A6B47_RS15265	51341..52672	+	1332	WP_087548826.1	Y-family DNA polymerase	-
A6B47_RS15270	52669..53019	+	351	WP_002399364.1	hypothetical protein	-
A6B47_RS15280	53270..53380	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	53420..53511	-	92	NuclAT_0	-	Antitoxin
-	53420..53511	-	92	NuclAT_0	-	Antitoxin
-	53420..53511	-	92	NuclAT_0	-	Antitoxin
-	53420..53511	-	92	NuclAT_0	-	Antitoxin
A6B47_RS15285	53620..53916	+	297	WP_002360665.1	replication control protein PrgN	-
A6B47_RS15290	54170..54952	+	783	WP_002360664.1	ParA family protein	-
A6B47_RS15295	54945..55301	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	prgB/asc10	1..55548	55548

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T63886 WP_002360667.1 NZ_CP015885:53270-53380 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T63886 NZ_CP015885:53270-53380 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin

Nucleotide

• Length: 92 bp

>AT63886 NZ_CP015885:c53511-53420 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin