Detailed information of TA system TA063880

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2777858..2778442
• Replicon: chromosome
• Accession: NZ_CP015883
• Organism: Enterococcus faecalis strain sorialis

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: A6B47_RS13795
• Protein ID: WP_002368507.1
• Coordinates: 2777858..2778055 (+)
• Length: 66 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2778205..2778442 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A6B47_RS13785	2773155..2773352	+	198	WP_002372618.1	putative holin-like toxin	-
A6B47_RS13790	2773542..2777315	-	3774	WP_025193481.1	WxL domain-containing protein	-
A6B47_RS13795	2777858..2778055	+	198	WP_002368507.1	putative holin-like toxin	Toxin
-	2778205..2778442	-	238	-	-	Antitoxin
A6B47_RS15505	2778442..2781447	-	3006	WP_168354157.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (32-65)

Sequences

Toxin

Protein

• Length: 66 a.a.
• Molecular weight: 7557.14 Da
• Isoelectric Point: 10.6710

>T63880 WP_002368507.1 NZ_CP015883:2777858-2778055 [Enterococcus faecalis]
MCREVMAVAIQSEREVMRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 198 bp

>T63880 NZ_CP015883:2777858-2778055 [Enterococcus faecalis]
ATGTGTAGAGAAGTTATGGCGGTGGCTATCCAATCTGAAAGAGAGGTGATGCGTATGCACGTATTTCCGAAATTTAGAGA
AAGGAGAGGCCTGTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGGTATGTTTACCATTGCTTTGATTGCGC
TGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 238 bp

>AT63880 NZ_CP015883:c2778442-2778205 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTATA
ATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACTTTTTGGATTATTT
AAAAATAACCGTACTGGTCAAAGTAAACGGTTATTTTTTCTTGTCTTCTTTAACAACCTTTAGGATTCCGAAGATTAA

Structures

Antitoxin