63868

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2772954..2773352 Replicon chromosome
Accession NZ_CP015883
Organism Enterococcus faecalis strain sorialis

Toxin (Protein)


Gene name txpA Uniprot ID A0A4U3MBY2
Locus tag A6B47_RS13785 Protein ID WP_002372618.1
Coordinates 2773155..2773352 (+) Length 66 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2772954..2773108 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6B47_RS13765 2768632..2769264 - 633 WP_002358972.1 RloB family protein -
A6B47_RS13770 2769273..2770568 - 1296 WP_002379013.1 AAA family ATPase -
A6B47_RS13780 2771030..2772646 + 1617 WP_002379014.1 phosphatase PAP2/LCP family protein -
- 2772954..2773108 - 155 - - Antitoxin
A6B47_RS13785 2773155..2773352 + 198 WP_002372618.1 putative holin-like toxin Toxin
A6B47_RS13790 2773542..2777315 - 3774 WP_025193481.1 WxL domain-containing protein -
A6B47_RS13795 2777858..2778055 + 198 WP_002368507.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(32-65)


Sequences

Toxin        


Download         Length: 66 a.a.        Molecular weight: 7516.13 Da        Isoelectric Point: 10.5649

>T63868 WP_002372618.1 NZ_CP015883:2773155-2773352 [Enterococcus faecalis]
MCREVMAVAIQSEREVMRMHVFPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 198 bp

>T63868 NZ_CP015883:2773155-2773352 [Enterococcus faecalis]
ATGTGTAGAGAAGTTATGGCGGTGGCTATCCAATCTGAAAGAGAGGTGATGCGTATGCACGTATTTCCGAAATTCACAGA
AAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGGTATGTTTACCATTGCTTTGATTGCGC
TGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 155 bp

>AT63868 NZ_CP015883:c2773108-2772954 [Enterococcus faecalis]
TTTTTAGGTAAGTGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGA
CGGTGACCTTTTGGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4U3MBY2

Antitoxin

Download structure file

References