63491

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2209268..2209484 Replicon chromosome
Accession NZ_CP015817
Organism Staphylococcus aureus strain FORC_039

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FORC39_RS11470 Protein ID WP_001802298.1
Coordinates 2209380..2209484 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2209268..2209323 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC39_RS11450 2205462..2206127 - 666 WP_001024095.1 SDR family oxidoreductase -
FORC39_RS11455 2206279..2206599 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FORC39_RS11460 2206601..2207581 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
FORC39_RS11465 2207847..2208938 + 1092 WP_000495681.1 hypothetical protein -
- 2209268..2209323 + 56 - - Antitoxin
FORC39_RS11470 2209380..2209484 - 105 WP_001802298.1 hypothetical protein Toxin
FORC39_RS11480 2210164..2210322 + 159 WP_001792784.1 hypothetical protein -
FORC39_RS11490 2210980..2211837 - 858 WP_000370928.1 Cof-type HAD-IIB family hydrolase -
FORC39_RS11495 2211905..2212687 - 783 WP_000908189.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-133)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T63491 WP_001802298.1 NZ_CP015817:c2209484-2209380 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T63491 NZ_CP015817:c2209484-2209380 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT63491 NZ_CP015817:2209268-2209323 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References