Detailed information of TA system TA063486

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1063382..1063562
• Replicon: chromosome
• Accession: NZ_CP015817
• Organism: Staphylococcus aureus strain FORC_039

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FORC39_RS14750
• Protein ID: WP_001801861.1
• Coordinates: 1063467..1063562 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1063382..1063439 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC39_RS05655	1059733..1060851	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
FORC39_RS05660	1061499..1061942	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
FORC39_RS05665	1062152..1062499	+	348	WP_001566695.1	DUF1433 domain-containing protein	-
FORC39_RS05670	1062521..1062895	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
FORC39_RS05675	1063083..1063265	+	183	Protein_1024	transposase	-
FORC39_RS05680	1063243..1063344	-	102	WP_001791232.1	hypothetical protein	-
-	1063382..1063439	+	58	-	-	Antitoxin
FORC39_RS14750	1063467..1063562	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
FORC39_RS05690	1064013..1064459	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
FORC39_RS05695	1065144..1065527	+	384	WP_000070811.1	hypothetical protein	-
FORC39_RS05700	1065538..1065714	+	177	WP_000375476.1	hypothetical protein	-
FORC39_RS05710	1066085..1066642	+	558	WP_000864138.1	ImmA/IrrE family metallo-endopeptidase	-
FORC39_RS14820	1066840..1067412	-	573	Protein_1031	hypothetical protein	-
FORC39_RS05715	1067513..1067854	-	342	WP_049311638.1	DUF3969 family protein	-
FORC39_RS05720	1067895..1068521	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	1043589..1089379	45790

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T63486 WP_001801861.1 NZ_CP015817:c1063562-1063467 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T63486 NZ_CP015817:c1063562-1063467 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT63486 NZ_CP015817:1063382-1063439 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin