Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2329074..2329576 Replicon chromosome
Accession NZ_CP015750
Organism Pectobacterium wasabiae CFBP 3304

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1D7Z1B6
Locus tag A7983_RS10540 Protein ID WP_005971141.1
Coordinates 2329074..2329328 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1D7Z1C0
Locus tag A7983_RS10545 Protein ID WP_005971140.1
Coordinates 2329325..2329576 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7983_RS10520 2324229..2325491 - 1263 WP_005971149.1 L-rhamnose isomerase -
A7983_RS10525 2325488..2326978 - 1491 WP_005971148.1 rhamnulokinase -
A7983_RS10530 2327314..2328153 + 840 WP_005971146.1 HTH-type transcriptional activator RhaS -
A7983_RS10535 2328178..2329032 + 855 WP_005971143.1 helix-turn-helix domain-containing protein -
A7983_RS10540 2329074..2329328 - 255 WP_005971141.1 Txe/YoeB family addiction module toxin Toxin
A7983_RS10545 2329325..2329576 - 252 WP_005971140.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
A7983_RS10550 2329651..2331342 - 1692 WP_005971138.1 ABC transporter ATP-binding protein -
A7983_RS10555 2331339..2332205 - 867 WP_005971136.1 ABC transporter permease -
A7983_RS10560 2332198..2333157 - 960 WP_039479078.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10185.72 Da        Isoelectric Point: 8.0659

>T63351 WP_005971141.1 NZ_CP015750:c2329328-2329074 [Pectobacterium wasabiae CFBP 3304]
VKLIWSEEAWEDHLYWQDIDKRIVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T63351 NZ_CP015750:c2329328-2329074 [Pectobacterium wasabiae CFBP 3304]
GTGAAGCTAATCTGGTCAGAAGAAGCATGGGAAGACCACCTGTACTGGCAGGATATCGATAAGCGGATAGTCAAAAAAAT
CAATGAATTAATAAAAGAAACGCGCAGAACGCCTTTTGAGGGAAAAGGAAAACCAGAGCCGCTTAAACATAATCTTGCTG
GTTTCTGGTCACGCCGTATCACCGAAGAACATCGTCTGGTCTATGCCATCACCGATGACGCCATGATGATCGCTGCTTGC
CGCTACCACTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9321.61 Da        Isoelectric Point: 4.6119

>AT63351 WP_005971140.1 NZ_CP015750:c2329576-2329325 [Pectobacterium wasabiae CFBP 3304]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNAIEGLKAGNGEERD
IIE

Download         Length: 252 bp

>AT63351 NZ_CP015750:c2329576-2329325 [Pectobacterium wasabiae CFBP 3304]
ATGCGTACAATTAGCTACAGCGAAGCCCGACAAAATCTATCAGCAACCATGATGAAAACGGTCGAAGACCGTGCTCCCAT
TCTTATCACCCGACAGAATGGTGAAGCCTGTGTGCTGATGTCTCTGGAAGAGTATAACTCTCTAGAAGAAACCGCGTATT
TACTGCGCTCGCCAGCGAATGCTAAAAGACTGATGAATGCAATCGAGGGCCTTAAGGCTGGTAATGGCGAAGAAAGAGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z1B6

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1C0

References