Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2289473..2289736 Replicon chromosome
Accession NZ_CP015646
Organism Staphylococcus aureus strain 08-02300

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag A7327_RS11475 Protein ID WP_001802298.1
Coordinates 2289632..2289736 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2289473..2289637 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7327_RS11455 2285713..2286378 - 666 WP_001024095.1 SDR family oxidoreductase -
A7327_RS11460 2286530..2286850 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
A7327_RS11465 2286852..2287835 + 984 WP_064626830.1 CDF family zinc efflux transporter CzrB -
A7327_RS11470 2288098..2289189 + 1092 WP_000495683.1 hypothetical protein -
- 2289473..2289637 + 165 - - Antitoxin
A7327_RS11475 2289632..2289736 - 105 WP_001802298.1 hypothetical protein Toxin
A7327_RS14545 2289897..2290380 - 484 Protein_2169 recombinase family protein -
A7327_RS11485 2290423..2291559 - 1137 WP_000115564.1 SAP domain-containing protein -
A7327_RS11490 2291848..2291940 + 93 WP_001790138.1 hypothetical protein -
A7327_RS11495 2292645..2293502 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
A7327_RS11500 2293570..2294352 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T63311 WP_001802298.1 NZ_CP015646:c2289736-2289632 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T63311 NZ_CP015646:c2289736-2289632 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT63311 NZ_CP015646:2289473-2289637 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References