Detailed information of TA system TA063185

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 27698..27846
• Replicon: plasmid pl21596-1
• Accession: NZ_CP015554
• Organism: Staphylococcus carnosus strain TMW 2.1596

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: A2I68_RS13235
• Protein ID: WP_011276848.1
• Coordinates: 27698..27793 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	27811..27846 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A2I68_RS13205 (23772)	23772..24764	+	993	WP_046100644.1	replication initiator protein A	-
A2I68_RS13210 (24803)	24803..24976	+	174	WP_046100645.1	protein rep	-
A2I68_RS13215 (25687)	25687..25857	+	171	WP_160149154.1	hypothetical protein	-
A2I68_RS13220 (25879)	25879..26307	+	429	WP_046100646.1	Hsp20/alpha crystallin family protein	-
A2I68_RS13225 (26612)	26612..26809	+	198	WP_039069675.1	helix-turn-helix transcriptional regulator	-
A2I68_RS13230 (26829)	26829..27371	+	543	WP_082080603.1	peptide deformylase	-
A2I68_RS13235 (27698)	27698..27793	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (27811)	27811..27846	+	36	NuclAT_0	-	Antitoxin
- (27811)	27811..27846	+	36	NuclAT_0	-	Antitoxin
- (27811)	27811..27846	+	36	NuclAT_0	-	Antitoxin
A2I68_RS13240 (28053)	28053..28385	-	333	WP_046100648.1	hypothetical protein	-
A2I68_RS13245 (28327)	28327..29811	-	1485	WP_052719494.1	retron Ec67 family RNA-directed DNA polymerase/endonuclease	-
A2I68_RS13250 (30059)	30059..30667	+	609	WP_046100649.1	recombinase family protein	-
A2I68_RS13255 (31036)	31036..32811	+	1776	WP_046100650.1	oleate hydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T63185 WP_011276848.1 NZ_CP015554:27698-27793 [Staphylococcus carnosus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T63185 NZ_CP015554:27698-27793 [Staphylococcus carnosus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT63185 NZ_CP015554:27811-27846 [Staphylococcus carnosus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin