Detailed information of TA system TA063056

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 2680990..2681205
• Replicon: chromosome
• Accession: NZ_CP015410
• Organism: Enterococcus faecalis strain KB1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: A4V06_RS13135
• Protein ID: WP_002360667.1
• Coordinates: 2681095..2681205 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2680990..2681054 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A4V06_RS13120	2676619..2676894	-	276	WP_065536085.1	type III secretion system protein PrgN	-
A4V06_RS13125	2676948..2677553	-	606	WP_000238804.1	recombinase family protein	-
A4V06_RS13130	2677684..2680656	+	2973	WP_000653331.1	Tn3 family transposase	-
-	2680990..2681054	+	65	-	-	Antitoxin
A4V06_RS13135	2681095..2681205	-	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
A4V06_RS13145	2681456..2681806	-	351	WP_010824125.1	hypothetical protein	-
A4V06_RS13150	2681803..2683131	-	1329	WP_002370254.1	Y-family DNA polymerase	-
A4V06_RS13155	2683560..2683862	-	303	WP_002406176.1	hypothetical protein	-
A4V06_RS13160	2683874..2684083	-	210	WP_010822384.1	hypothetical protein	-
A4V06_RS13165	2684144..2684368	-	225	WP_002406593.1	hypothetical protein	-
A4V06_RS13170	2684362..2684676	-	315	WP_025188489.1	hypothetical protein	-
A4V06_RS13175	2684666..2685286	-	621	WP_025188285.1	recombinase family protein	-
A4V06_RS13180	2685489..2685803	-	315	WP_002401837.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2667127..2708128	41001

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T63056 WP_002360667.1 NZ_CP015410:c2681205-2681095 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T63056 NZ_CP015410:c2681205-2681095 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT63056 NZ_CP015410:2680990-2681054 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin