Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1791583..1792279 Replicon chromosome
Accession NZ_CP015379
Organism Hafnia alvei strain HUMV-5920

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag A6V27_RS08195 Protein ID WP_063586233.1
Coordinates 1791583..1791894 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A097R796
Locus tag A6V27_RS08200 Protein ID WP_025799364.1
Coordinates 1791881..1792279 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6V27_RS08170 1787592..1788350 + 759 WP_063586231.1 glycerophosphodiester phosphodiesterase -
A6V27_RS08175 1788603..1789034 - 432 WP_040046470.1 hypothetical protein -
A6V27_RS08180 1789308..1789637 + 330 WP_040046471.1 thiosulfate sulfurtransferase GlpE -
A6V27_RS08185 1789686..1790522 + 837 WP_063586232.1 rhomboid family intramembrane serine protease GlpG -
A6V27_RS08190 1790569..1791327 + 759 WP_025799366.1 DeoR/GlpR family transcriptional regulator -
A6V27_RS08195 1791583..1791894 + 312 WP_063586233.1 type II toxin-antitoxin system MqsR family toxin Toxin
A6V27_RS08200 1791881..1792279 + 399 WP_025799364.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
A6V27_RS08205 1792522..1794006 + 1485 WP_063586234.1 glycerol-3-phosphate dehydrogenase -
A6V27_RS08210 1794267..1796714 - 2448 WP_046360079.1 glycogen phosphorylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12047.94 Da        Isoelectric Point: 7.4755

>T62953 WP_063586233.1 NZ_CP015379:1791583-1791894 [Hafnia alvei]
MEKRTPHSSLEKVRNLVGKGMVRITKSAHRDAELMHFGLADMYRVVCELSPQDFYKSMTTYDDHRIWQDVYHCHLDKVSL
YVKLTVVDDVLIVSFKELNHALP

Download         Length: 312 bp

>T62953 NZ_CP015379:1791583-1791894 [Hafnia alvei]
ATGGAGAAGCGAACGCCGCATTCTAGCTTAGAAAAGGTACGGAACTTGGTTGGGAAGGGGATGGTTAGGATAACCAAATC
AGCGCACCGCGATGCTGAACTGATGCATTTTGGCCTAGCTGATATGTATCGCGTTGTCTGTGAGCTTTCGCCTCAAGATT
TCTATAAGAGTATGACAACTTACGATGACCATCGTATTTGGCAGGATGTTTACCATTGCCATCTGGACAAGGTGTCTCTC
TATGTGAAATTAACGGTTGTTGATGATGTCCTCATCGTTTCATTTAAGGAGTTAAATCATGCACTGCCCTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14759.92 Da        Isoelectric Point: 5.7723

>AT62953 WP_025799364.1 NZ_CP015379:1791881-1792279 [Hafnia alvei]
MHCPECGSKNTIKDYRDIPFTYKGQSTVVKAVGADWCLDCGEGVIFKDESLRIDSILTEFNKQVNASIIDPEYVVAMRKK
LNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKYPELLEEIRN

Download         Length: 399 bp

>AT62953 NZ_CP015379:1791881-1792279 [Hafnia alvei]
ATGCACTGCCCTGAATGTGGTTCGAAAAATACGATTAAAGATTACCGTGACATCCCATTTACCTATAAAGGGCAGTCTAC
AGTGGTTAAAGCTGTGGGGGCAGATTGGTGTTTAGACTGCGGTGAAGGCGTAATTTTTAAAGACGAATCTCTGCGTATCG
ACAGCATTTTGACGGAGTTCAATAAGCAGGTTAATGCGTCCATTATCGATCCTGAGTACGTAGTGGCGATGCGAAAAAAG
CTGAACCTTTCCCAAAGTGAAGCCGGTGAGATTTTTGGTGGCGGCGTAAATGCATTTTCGCGCTACGAAACAGGCAAGGC
GCTGCCCCATGTATCGACCATCAAGCTGTTAAAACTGCTTGATAAGTATCCAGAATTGCTCGAAGAAATTCGTAACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A097R796

References