Detailed information of TA system TA062932

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2542079..2542394
• Replicon: chromosome
• Accession: NZ_CP015375
• Organism: Bacillus subtilis subsp. subtilis strain KCTC 3135

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: AS891_RS22945
• Protein ID: WP_120322743.1
• Coordinates: 2542233..2542394 (-)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2542079..2542252 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AS891_RS13770	2537993..2538550	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
AS891_RS13775	2538652..2540454	+	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
AS891_RS13780	2540464..2540922	+	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
AS891_RS13785	2541122..2541964	+	843	WP_003231327.1	hypothetical protein	-
-	2542079..2542252	+	174	-	-	Antitoxin
AS891_RS22945	2542233..2542394	-	162	WP_120322743.1	putative holin-like toxin	Toxin
AS891_RS13790	2542614..2542946	+	333	WP_026009814.1	hypothetical protein	-
AS891_RS13795	2543179..2546784	+	3606	WP_004399367.1	membrane protein	-
AS891_RS13800	2546831..2547166	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2533582..2566279	32697

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T62932 WP_120322743.1 NZ_CP015375:c2542394-2542233 [Bacillus subtilis subsp. subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T62932 NZ_CP015375:c2542394-2542233 [Bacillus subtilis subsp. subtilis]
ATTTCCTGTACAGTAAGTTTTGCTCACTCGAGGGAGTCTTGCTCATCCCCTAATGAAAGGGGTGATGCTATGTCAACATT
CCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAATAGACCTCCCTT
GA

Antitoxin

Nucleotide

• Length: 174 bp

>AT62932 NZ_CP015375:2542079-2542252 [Bacillus subtilis subsp. subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin