Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2009187..2009886 Replicon chromosome
Accession NZ_CP015202
Organism Pseudomonas putida B6-2

Toxin (Protein)


Gene name mqsR Uniprot ID A0A550F6I7
Locus tag KKK_RS09145 Protein ID WP_019750831.1
Coordinates 2009590..2009886 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7D5VVT2
Locus tag KKK_RS09140 Protein ID WP_029380550.1
Coordinates 2009187..2009588 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KKK_RS30795 2004764..2005250 - 487 Protein_1815 efflux RND transporter periplasmic adaptor subunit -
KKK_RS09125 2005242..2006147 - 906 Protein_1816 FAD-binding protein -
KKK_RS09130 2006148..2006897 - 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
KKK_RS09135 2007433..2009115 + 1683 WP_023389616.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
KKK_RS09140 2009187..2009588 - 402 WP_029380550.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KKK_RS09145 2009590..2009886 - 297 WP_019750831.1 type II toxin-antitoxin system MqsR family toxin Toxin
KKK_RS09150 2009981..2011306 - 1326 WP_019750830.1 MFS transporter -
KKK_RS09155 2011379..2011858 - 480 WP_019750829.1 hypothetical protein -
KKK_RS09160 2012027..2012503 - 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
KKK_RS09165 2012625..2014250 - 1626 WP_003254243.1 twin-arginine translocation signal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11094.88 Da        Isoelectric Point: 9.8759

>T62613 WP_019750831.1 NZ_CP015202:c2009886-2009590 [Pseudomonas putida B6-2]
MEKRTPHCPLHRLQVLLSQGKVRTTQAATLGARSLGLGPYDMLDVVRGLSPGDFHKSMTSYNDHRIWQDVYRAQTAVGRV
YLKLTVVDDLLILSFKEL

Download         Length: 297 bp

>T62613 NZ_CP015202:c2009886-2009590 [Pseudomonas putida B6-2]
ATGGAAAAGAGAACGCCTCACTGCCCTTTGCATCGGCTGCAAGTGCTATTGAGCCAAGGAAAGGTACGTACCACCCAGGC
GGCGACCCTGGGAGCGCGGTCGCTTGGGCTAGGTCCCTATGACATGTTGGATGTTGTCCGCGGGCTATCGCCAGGTGACT
TCCATAAAAGTATGACGAGCTACAACGATCATCGTATTTGGCAGGATGTCTATCGGGCGCAAACCGCCGTAGGCAGGGTT
TACCTCAAGCTGACGGTGGTCGACGATCTGCTCATCCTATCTTTCAAGGAGCTTTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14692.91 Da        Isoelectric Point: 4.9749

>AT62613 WP_029380550.1 NZ_CP015202:c2009588-2009187 [Pseudomonas putida B6-2]
MKCPLCGGAELVAQSRDMPYRYKGEATVIPDIFGDYCPTCGEAVLGMDEAQRMSDLMTAFERKVNAAVVDPGFIAAMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT62613 NZ_CP015202:c2009588-2009187 [Pseudomonas putida B6-2]
ATGAAATGTCCCCTATGTGGAGGAGCTGAGTTGGTTGCGCAGTCGCGAGACATGCCGTATCGCTACAAAGGTGAGGCGAC
CGTCATCCCGGACATCTTTGGTGACTACTGCCCGACGTGTGGCGAGGCGGTACTGGGCATGGACGAGGCCCAGCGTATGA
GTGATCTGATGACGGCGTTTGAGCGCAAGGTCAATGCAGCCGTTGTCGATCCCGGCTTCATTGCTGCCATGCGCAGAAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATCTTCGGTGGTGGGGTCAATGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACCCCGCCAGTGGCATTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTTGAGGAAGTGCGTACTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A550F6I7

Antitoxin

Source ID Structure
AlphaFold DB A0A7D5VVT2

References