Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 3862381..3862602 | Replicon | chromosome |
Accession | NZ_CP015138 | ||
Organism | Escherichia coli strain Ecol_732 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | A0A1U9U3P9 |
Locus tag | A4X18_RS18890 | Protein ID | WP_001531632.1 |
Coordinates | 3862381..3862488 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 3862536..3862602 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A4X18_RS18865 | 3858225..3859307 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
A4X18_RS18870 | 3859307..3860140 | + | 834 | WP_000456450.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
A4X18_RS18875 | 3860137..3860529 | + | 393 | WP_000200375.1 | invasion regulator SirB2 | - |
A4X18_RS18880 | 3860533..3861342 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
A4X18_RS18885 | 3861378..3862232 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
A4X18_RS18890 | 3862381..3862488 | - | 108 | WP_001531632.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- | 3862536..3862602 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_10 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_5 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_6 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_7 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_8 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 3862536..3862602 | + | 67 | NuclAT_9 | - | Antitoxin |
- | 3862538..3862601 | + | 64 | NuclAT_12 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_12 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_12 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_12 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_13 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_13 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_13 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_13 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_14 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_14 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_14 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_14 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_15 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_15 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_15 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_15 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_16 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_16 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_16 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_16 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_17 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_17 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_17 | - | - |
- | 3862538..3862601 | + | 64 | NuclAT_17 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_18 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_18 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_18 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_18 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_19 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_19 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_19 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_19 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_20 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_20 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_20 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_20 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_21 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_21 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_21 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_21 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_22 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_22 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_22 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_22 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_23 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_23 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_23 | - | - |
- | 3862538..3862603 | + | 66 | NuclAT_23 | - | - |
A4X18_RS18895 | 3862893..3863993 | - | 1101 | WP_000063608.1 | sodium-potassium/proton antiporter ChaA | - |
A4X18_RS18900 | 3864263..3864502 | + | 240 | WP_000120702.1 | putative cation transport regulator ChaB | - |
A4X18_RS18905 | 3864651..3865346 | + | 696 | WP_001295621.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
A4X18_RS18910 | 3865390..3865743 | - | 354 | WP_001169659.1 | DsrE/F sulfur relay family protein YchN | - |
A4X18_RS18915 | 3865928..3867322 | + | 1395 | WP_000086187.1 | inverse autotransporter invasin YchO | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4040.89 Da Isoelectric Point: 12.5163
>T62486 WP_001531632.1 NZ_CP015138:c3862488-3862381 [Escherichia coli]
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK
Download Length: 108 bp
>T62486 NZ_CP015138:c3862488-3862381 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 67 bp
>AT62486 NZ_CP015138:3862536-3862602 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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