Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4852045..4852758 Replicon chromosome
Accession NZ_CP015136
Organism Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LuPra_RS20230 Protein ID WP_157899458.1
Coordinates 4852045..4852401 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LuPra_RS20235 Protein ID WP_110172424.1
Coordinates 4852405..4852758 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LuPra_RS20205 4849218..4850378 + 1161 WP_201792161.1 PLP-dependent aspartate aminotransferase family protein -
LuPra_RS20210 4850554..4850943 - 390 WP_110172420.1 divalent-cation tolerance protein CutA -
LuPra_RS20215 4850970..4851353 + 384 WP_157899456.1 septum formation initiator family protein -
LuPra_RS32115 4851478..4851897 - 420 WP_157899457.1 hypothetical protein -
LuPra_RS20230 4852045..4852401 + 357 WP_157899458.1 toxin Toxin
LuPra_RS20235 4852405..4852758 + 354 WP_110172424.1 helix-turn-helix domain-containing protein Antitoxin
LuPra_RS20240 4852956..4853873 - 918 WP_110172425.1 hypothetical protein -
LuPra_RS20245 4854120..4855922 + 1803 WP_162271457.1 PD40 domain-containing protein -
LuPra_RS20250 4856249..4857184 - 936 WP_110172427.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4851991..4874180 22189


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(54-94)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13358.34 Da        Isoelectric Point: 10.1512

>T62446 WP_157899458.1 NZ_CP015136:4852045-4852401 [Luteitalea pratensis]
VESIEAPTFTAMVAGYLEDDEYRALQLFLAGDPEAGDVMPGTGGFRKLRWADRRRGKGKRGGLRVIYYHLSADAQIWLMT
LYDKDEMADLSAAEKRALKAALEAELARRAARRRLRRK

Download         Length: 357 bp

>T62446 NZ_CP015136:4852045-4852401 [Luteitalea pratensis]
GTGGAGTCCATCGAGGCTCCCACGTTTACAGCGATGGTCGCGGGCTACCTGGAGGACGATGAATATCGAGCGTTGCAGCT
GTTCCTGGCGGGGGATCCGGAGGCGGGCGATGTCATGCCGGGCACCGGCGGCTTTCGTAAGCTGCGATGGGCCGATCGGC
GCCGAGGCAAGGGCAAGCGTGGTGGCCTCAGGGTGATCTACTACCACCTTTCGGCAGATGCTCAGATCTGGCTGATGACG
CTCTACGACAAGGACGAAATGGCCGACCTGAGCGCCGCTGAGAAACGGGCTTTGAAGGCGGCTCTCGAGGCCGAACTTGC
GCGGCGTGCCGCGCGCCGCCGGCTACGAAGGAAGTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13534.80 Da        Isoelectric Point: 11.7883

>AT62446 WP_110172424.1 NZ_CP015136:4852405-4852758 [Luteitalea pratensis]
MAAKKRPVARNKRSLFRELMSGVEAMRDHREGRLTLRTREMQPITVPPINADVVRETREALKMSRHVFAFKIGVNPRTLE
RWEQGRSKPNEQAAALIWLVRKYPDTLKRLESLAASA

Download         Length: 354 bp

>AT62446 NZ_CP015136:4852405-4852758 [Luteitalea pratensis]
ATGGCAGCGAAGAAGCGACCCGTGGCACGAAATAAGCGCAGCCTCTTCCGAGAACTCATGTCGGGTGTGGAGGCTATGCG
GGATCACCGCGAAGGGCGGCTCACCTTAAGGACACGAGAGATGCAGCCGATCACGGTTCCGCCAATCAACGCGGACGTTG
TCCGCGAGACGCGCGAGGCGCTCAAGATGTCGCGTCACGTGTTTGCATTCAAGATTGGTGTGAACCCCCGCACGCTCGAG
CGATGGGAACAGGGACGGAGCAAACCGAACGAGCAGGCTGCCGCCTTGATTTGGCTGGTGCGGAAATATCCCGACACGCT
CAAGCGGTTAGAGTCGCTCGCAGCCTCAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References