Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4852045..4852758 Replicon chromosome
Accession NZ_CP015136
Organism Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LuPra_RS20230 Protein ID WP_157899458.1
Coordinates 4852045..4852401 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LuPra_RS20235 Protein ID WP_110172424.1
Coordinates 4852405..4852758 (+) Length 118 a.a.

Genomic Context

LuPra_RS20205LuPra_RS20215LuPra_RS20230LuPra_RS20235LuPra_RS20245LuPra_RS20210LuPra_RS32115LuPra_RS20240LuPra_RS20250
Location: 4849218..4850378 (1161 bp)
Type: Others
Protein ID: WP_201792161.1
Location: 4850970..4851353 (384 bp)
Type: Others
Protein ID: WP_157899456.1
Location: 4852045..4852401 (357 bp)
Type: Toxin
Protein ID: WP_157899458.1
Location: 4852405..4852758 (354 bp)
Type: Antitoxin
Protein ID: WP_110172424.1
Location: 4854120..4855922 (1803 bp)
Type: Others
Protein ID: WP_162271457.1
Location: 4850554..4850943 (390 bp)
Type: Others
Protein ID: WP_110172420.1
Location: 4851478..4851897 (420 bp)
Type: Others
Protein ID: WP_157899457.1
Location: 4852956..4853873 (918 bp)
Type: Others
Protein ID: WP_110172425.1
Location: 4856249..4857184 (936 bp)
Type: Others
Protein ID: WP_110172427.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LuPra_RS202054849218..4850378+1161WP_201792161.1PLP-dependent aspartate aminotransferase family protein-
LuPra_RS202104850554..4850943-390WP_110172420.1divalent-cation tolerance protein CutA-
LuPra_RS202154850970..4851353+384WP_157899456.1septum formation initiator family protein-
LuPra_RS321154851478..4851897-420WP_157899457.1hypothetical protein-
LuPra_RS202304852045..4852401+357WP_157899458.1toxinToxin
LuPra_RS202354852405..4852758+354WP_110172424.1helix-turn-helix domain-containing proteinAntitoxin
LuPra_RS202404852956..4853873-918WP_110172425.1hypothetical protein-
LuPra_RS202454854120..4855922+1803WP_162271457.1PD40 domain-containing protein-
LuPra_RS202504856249..4857184-936WP_110172427.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--4851991..487418022189


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(54-94)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13358.34 Da        Isoelectric Point: 10.1512

>T62446 WP_157899458.1 NZ_CP015136:4852045-4852401 [Luteitalea pratensis]
VESIEAPTFTAMVAGYLEDDEYRALQLFLAGDPEAGDVMPGTGGFRKLRWADRRRGKGKRGGLRVIYYHLSADAQIWLMT
LYDKDEMADLSAAEKRALKAALEAELARRAARRRLRRK

Download         Length: 357 bp

>T62446 NZ_CP015136:4852045-4852401 [Luteitalea pratensis]
GTGGAGTCCATCGAGGCTCCCACGTTTACAGCGATGGTCGCGGGCTACCTGGAGGACGATGAATATCGAGCGTTGCAGCT
GTTCCTGGCGGGGGATCCGGAGGCGGGCGATGTCATGCCGGGCACCGGCGGCTTTCGTAAGCTGCGATGGGCCGATCGGC
GCCGAGGCAAGGGCAAGCGTGGTGGCCTCAGGGTGATCTACTACCACCTTTCGGCAGATGCTCAGATCTGGCTGATGACG
CTCTACGACAAGGACGAAATGGCCGACCTGAGCGCCGCTGAGAAACGGGCTTTGAAGGCGGCTCTCGAGGCCGAACTTGC
GCGGCGTGCCGCGCGCCGCCGGCTACGAAGGAAGTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13534.80 Da        Isoelectric Point: 11.7883

>AT62446 WP_110172424.1 NZ_CP015136:4852405-4852758 [Luteitalea pratensis]
MAAKKRPVARNKRSLFRELMSGVEAMRDHREGRLTLRTREMQPITVPPINADVVRETREALKMSRHVFAFKIGVNPRTLE
RWEQGRSKPNEQAAALIWLVRKYPDTLKRLESLAASA

Download         Length: 354 bp

>AT62446 NZ_CP015136:4852405-4852758 [Luteitalea pratensis]
ATGGCAGCGAAGAAGCGACCCGTGGCACGAAATAAGCGCAGCCTCTTCCGAGAACTCATGTCGGGTGTGGAGGCTATGCG
GGATCACCGCGAAGGGCGGCTCACCTTAAGGACACGAGAGATGCAGCCGATCACGGTTCCGCCAATCAACGCGGACGTTG
TCCGCGAGACGCGCGAGGCGCTCAAGATGTCGCGTCACGTGTTTGCATTCAAGATTGGTGTGAACCCCCGCACGCTCGAG
CGATGGGAACAGGGACGGAGCAAACCGAACGAGCAGGCTGCCGCCTTGATTTGGCTGGTGCGGAAATATCCCGACACGCT
CAAGCGGTTAGAGTCGCTCGCAGCCTCAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References