Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 610811..611461 Replicon chromosome
Accession NZ_CP015099
Organism Glaesserella parasuis strain SC1401

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag A4U84_RS02720 Protein ID WP_062923967.1
Coordinates 610811..611149 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag A4U84_RS02725 Protein ID WP_021117805.1
Coordinates 611153..611461 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4U84_RS02680 606435..606809 + 375 WP_021111694.1 cytochrome b562 family protein -
A4U84_RS02685 606930..607845 + 916 Protein_546 transposase -
A4U84_RS10995 607800..608066 + 267 Protein_547 cation-transporting ATPase PacS -
A4U84_RS02695 608533..609972 - 1440 WP_062923966.1 glutamate--tRNA ligase -
A4U84_RS02720 610811..611149 + 339 WP_062923967.1 toxin Toxin
A4U84_RS02725 611153..611461 + 309 WP_021117805.1 helix-turn-helix domain-containing protein Antitoxin
A4U84_RS02730 611662..612822 + 1161 WP_010786053.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
A4U84_RS02735 612922..613503 + 582 WP_005710402.1 type IV pilus biogenesis/stability protein PilW -
A4U84_RS02740 613564..614499 + 936 WP_005710401.1 KpsF/GutQ family sugar-phosphate isomerase -
A4U84_RS02745 614499..614987 + 489 WP_005710400.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13244.26 Da        Isoelectric Point: 9.8649

>T62337 WP_062923967.1 NZ_CP015099:610811-611149 [Glaesserella parasuis]
MNVAFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVQGKQVWL
FHAYNKNQQDDLSNEERVVLANTLSYLKSLVR

Download         Length: 339 bp

>T62337 NZ_CP015099:610811-611149 [Glaesserella parasuis]
ATGAATGTCGCTTTTGTGGAGTTGCCGCCTTTTGAGGAATATAGAAAAAAGTATCTTGACGATGACACATTTAGATTATT
ACAAAATGAGTTATTAAAATTTCCCGATAAGGGAGAGCTTATTCAAGGTACTGGGGGACTAAGAAAATTGCGTATTGTGG
ATATTATTAGACAAAAAGGAAAAAGAGGCGGAGCTAGGGTAATCTATTACTATTATGTACAAGGGAAACAAGTTTGGTTG
TTCCATGCCTATAATAAAAACCAACAAGACGATTTATCTAATGAAGAACGTGTGGTTTTGGCGAATACATTAAGCTATTT
AAAATCTTTAGTGAGGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11553.68 Da        Isoelectric Point: 10.4294

>AT62337 WP_021117805.1 NZ_CP015099:611153-611461 [Glaesserella parasuis]
MGKLFNELMEGMQALELHLKGKITLKTTVVEIPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp

>AT62337 NZ_CP015099:611153-611461 [Glaesserella parasuis]
ATGGGAAAATTATTTAATGAACTAATGGAAGGGATGCAAGCATTAGAGTTGCATTTAAAAGGCAAAATCACATTAAAAAC
CACTGTCGTAGAAATTCCGGATCCGATAGTAATTACCCCTGAAGAAGTGAAAGCTATTCGCCAAAAATTAAATCTTTCAC
AAGCGGTTTTTGCTCGTAAATTACACACTTCGGTGAGAACTTATCAAGGCTGGGAGCAAGGAAGAACAAAGCCCAATCCG
CAAGCGGTCTTACTATTAAAAATGGTTGAAAAATCGCCAAAAACATTTGAGCAAATTGCGAGCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References