61873

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4946361..4947061 Replicon chromosome
Accession NZ_CP014870
Organism Pseudomonas silesiensis strain A3

Toxin (Protein)


Gene name mqsR Uniprot ID A0A191YXN6
Locus tag PMA3_RS21855 Protein ID WP_064679137.1
Coordinates 4946361..4946657 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A191YY32
Locus tag PMA3_RS21860 Protein ID WP_064679138.1
Coordinates 4946660..4947061 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMA3_RS21830 4942223..4942579 + 357 WP_064679132.1 4a-hydroxytetrahydrobiopterin dehydratase -
PMA3_RS21835 4942579..4943772 + 1194 WP_064679133.1 aspartate/tyrosine/aromatic aminotransferase -
PMA3_RS21840 4944276..4944461 + 186 WP_064679134.1 hypothetical protein -
PMA3_RS21845 4944562..4945776 + 1215 WP_064679135.1 MFS transporter -
PMA3_RS21850 4945773..4946186 - 414 WP_064679136.1 aminoacyl-tRNA hydrolase -
PMA3_RS21855 4946361..4946657 + 297 WP_064679137.1 type II toxin-antitoxin system MqsR family toxin Toxin
PMA3_RS21860 4946660..4947061 + 402 WP_064679138.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PMA3_RS21865 4947295..4948077 + 783 WP_064679139.1 NAD(P)H-dependent oxidoreductase -
PMA3_RS21870 4948154..4949572 - 1419 WP_064679140.1 amino acid permease -
PMA3_RS21875 4950449..4951747 - 1299 WP_064679141.1 pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Zinc finger, MqsA-type

(3-47)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11079.86 Da        Isoelectric Point: 6.7166

>T61873 WP_064679137.1 NZ_CP014870:4946361-4946657 [Pseudomonas silesiensis]
MEKRTPHCKLSTVKILIEEGKVRTTQAARVGANELGLDLSEMLRVVMALTPTDFYKSMTTHADHTIWQDVYRPSTQAGDV
YLKLTVIDDVLIVSFKEL

Download         Length: 297 bp

>T61873 NZ_CP014870:4946361-4946657 [Pseudomonas silesiensis]
ATGGAAAAAAGAACCCCTCACTGCAAGCTATCTACCGTCAAAATCTTGATCGAGGAGGGTAAGGTACGCACAACGCAAGC
GGCGCGAGTTGGAGCGAATGAGCTGGGGCTTGATCTGTCTGAAATGCTGAGGGTGGTAATGGCGCTCACACCAACTGATT
TCTACAAAAGCATGACCACTCATGCCGATCACACGATTTGGCAAGACGTGTACCGCCCAAGCACACAAGCAGGCGACGTG
TATCTGAAACTGACGGTTATTGATGACGTGCTGATCGTATCCTTTAAGGAGCTATAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14687.99 Da        Isoelectric Point: 6.4566

>AT61873 WP_064679138.1 NZ_CP014870:4946660-4947061 [Pseudomonas silesiensis]
MKCPVCGAAELIHDTRDLPYTYKGETTFIAAVTGDFCPACAESVLDAVESDRVMREMRGFSKQINAAIVDPGFITTVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTKPPLALIKLLKVLDRHPELLNEVRMA

Download         Length: 402 bp

>AT61873 NZ_CP014870:4946660-4947061 [Pseudomonas silesiensis]
ATGAAATGTCCTGTTTGCGGCGCCGCTGAACTCATCCATGACACCCGCGACCTGCCGTATACCTACAAAGGTGAAACCAC
TTTCATTGCGGCGGTGACTGGCGATTTTTGCCCAGCCTGTGCCGAGTCTGTCCTGGATGCAGTTGAGTCGGATCGTGTCA
TGCGTGAAATGCGTGGGTTCTCGAAGCAGATCAATGCGGCCATTGTCGACCCGGGCTTTATCACGACCGTGCGCAAAAAG
CTCGATCTTGACCAGCGTGAGGCGGCAGAAATTTTCGGGGGCGGAGTTAATGCGTTCTCGCGCTATGAGAATGGCAAGAC
CAAGCCCCCATTGGCCCTGATCAAGCTGCTCAAGGTGCTTGATCGTCACCCCGAACTGTTGAACGAAGTCAGGATGGCAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A191YXN6

Antitoxin

Source ID Structure
AlphaFold DB A0A191YY32

References