61846

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) orf9-orf10/-
Location 163661..165045 Replicon plasmid unnamed
Accession NZ_CP014857
Organism Lysinibacillus sphaericus strain III(3)7

Toxin (Protein)


Gene name ORF9 Uniprot ID -
Locus tag A1T07_RS23550 Protein ID WP_012291646.1
Coordinates 164500..165045 (-) Length 182 a.a.

Antitoxin (Protein)


Gene name ORF10 Uniprot ID B1I081
Locus tag A1T07_RS23545 Protein ID WP_012291647.1
Coordinates 163661..164500 (-) Length 280 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A1T07_RS23520 160224..160502 - 279 WP_155726290.1 hypothetical protein -
A1T07_RS23525 160544..161266 - 723 WP_062794090.1 hypothetical protein -
A1T07_RS23530 161707..162075 - 369 WP_031417274.1 hypothetical protein -
A1T07_RS23535 162363..162638 - 276 WP_041659272.1 hypothetical protein -
A1T07_RS23540 162683..163534 - 852 WP_061504576.1 hypothetical protein -
A1T07_RS23545 163661..164500 - 840 WP_012291647.1 hypothetical protein Antitoxin
A1T07_RS23550 164500..165045 - 546 WP_012291646.1 NYN domain-containing protein Toxin
A1T07_RS23555 165266..165754 - 489 WP_012291645.1 hypothetical protein -
A1T07_RS23560 165794..166345 - 552 WP_145912405.1 ATP-binding protein -
A1T07_RS23565 166332..166607 - 276 WP_031417270.1 DUF1292 domain-containing protein -
A1T07_RS23570 166618..167754 - 1137 WP_012291642.1 hypothetical protein -
A1T07_RS23575 167758..168852 - 1095 WP_041659270.1 hypothetical protein -
A1T07_RS23580 169041..169796 - 756 WP_012291640.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - - 1..173793 173793


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

NYN domain

(4-158)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 182 a.a.        Molecular weight: 20304.38 Da        Isoelectric Point: 9.4376

>T61846 WP_012291646.1 NZ_CP014857:c165045-164500 [Lysinibacillus sphaericus]
MKKTAILVDEMNVIQQLRRLGIHGFNPWNAFYQALQRWNGDKKGVKAFYCANVPKEDAEHEKRNNFFEGLINHNIKVSVG
TVVYDSNSRRIAKGVDVALALDIVEHARSGVQDIFICTGDADVVPAIIRAQELGSRVHVVVSRAIPAKNITLAADSVVRL
EDILETMPPHRIKYFAKERVS

Download         Length: 546 bp

>T61846 NZ_CP014857:c165045-164500 [Lysinibacillus sphaericus]
ATGAAAAAGACAGCTATTTTAGTAGATGAAATGAACGTGATTCAACAACTCCGACGTTTAGGAATCCATGGATTCAATCC
CTGGAATGCATTTTATCAGGCGTTACAACGTTGGAATGGTGATAAGAAAGGTGTTAAAGCATTTTATTGTGCTAACGTAC
CTAAAGAAGATGCAGAACATGAAAAGCGTAATAATTTCTTTGAAGGATTAATAAATCATAACATCAAAGTATCAGTAGGT
ACTGTTGTATATGACTCAAACTCAAGACGGATAGCAAAAGGTGTAGATGTTGCCTTAGCGCTGGACATAGTAGAACATGC
TAGAAGCGGTGTACAAGATATTTTCATCTGTACAGGTGATGCTGATGTTGTGCCTGCCATTATTCGCGCACAGGAGCTCG
GTAGTCGTGTTCACGTTGTAGTTTCCAGGGCTATCCCAGCTAAAAATATCACCCTTGCAGCTGATTCAGTGGTTAGATTA
GAGGATATCTTAGAAACCATGCCTCCTCACCGCATTAAATACTTTGCTAAGGAGCGTGTGAGCTAA

Antitoxin


Download         Length: 280 a.a.        Molecular weight: 31528.09 Da        Isoelectric Point: 5.2827

>AT61846 WP_012291647.1 NZ_CP014857:c164500-163661 [Lysinibacillus sphaericus]
METAPQEIFDLTLAKKTENEKELENAYRRIPDEYHDFIVLLEQKIKITDSRYFLAEEFITMGAYQDEKGIYLKIKKPYMT
VDGRIRMARDEHSKKEAKLIISEPQIIQVGNRICMNVTVESEIHGTATGTIEVNINGFGVDKKNPVANAQTSALGRALGF
LGYGIIGTAATASLDEATNLYNSLFASPSKEQVDPKKPEIKRVRICGPIEYKNNDLGYVQIQLETEEYVIMQIGKSLFRY
ENILVTNAVVKVRGWWNGEIFAAAPDQDIILDQNKKIVS

Download         Length: 840 bp

>AT61846 NZ_CP014857:c164500-163661 [Lysinibacillus sphaericus]
ATGGAGACAGCGCCACAAGAGATATTTGACCTTACACTTGCCAAAAAGACTGAAAATGAAAAGGAATTAGAGAATGCTTA
CAGAAGGATTCCGGATGAATACCATGACTTTATTGTATTGCTGGAGCAAAAAATTAAAATTACTGATAGTAGATACTTTT
TAGCAGAGGAATTTATAACAATGGGTGCCTACCAAGACGAAAAAGGTATCTATTTAAAGATTAAAAAGCCGTATATGACT
GTTGATGGCCGTATTCGAATGGCTCGCGATGAACATTCTAAAAAGGAAGCCAAACTAATTATTTCTGAACCTCAAATTAT
ACAAGTGGGAAATCGAATTTGTATGAATGTGACAGTTGAAAGTGAAATCCATGGCACTGCTACAGGAACTATAGAGGTTA
ATATTAACGGTTTTGGGGTAGATAAGAAGAATCCTGTAGCTAACGCACAAACTAGCGCTTTAGGACGTGCATTAGGCTTT
TTAGGGTACGGTATTATAGGTACTGCAGCAACCGCTTCATTAGATGAGGCTACAAACCTATATAACTCTTTATTTGCTTC
TCCAAGTAAGGAACAAGTTGATCCAAAGAAACCCGAGATTAAACGAGTTAGAATTTGTGGACCGATCGAATATAAAAACA
ACGACTTAGGGTATGTTCAAATACAGCTAGAAACTGAGGAATATGTAATAATGCAAATTGGAAAAAGCTTATTCAGATAT
GAAAATATACTGGTAACAAATGCAGTAGTAAAGGTGCGTGGTTGGTGGAACGGTGAAATATTCGCAGCTGCACCTGACCA
GGATATTATCTTGGACCAAAATAAAAAGATTGTTTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6H0A0V0

References